Antaeus labs: Hydra Head Six

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Hydra Head Six 120 Capsules

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Anti-catabolic stops muscle loss via 6 pathways!
  • First supplement of its kind that prevents muscle loss
  • An Anti-Catabolic, Hydra Head Six stops muscle being broken down
  • Targets six different pathways by which muscle can be lost when dieting
  • Inhibits cortisol mediated muscle loss
  • Promotes muscle hypertrophy and hyperplasia, the growing of new muscle cells
  • Reduces free radical damage caused by oxidation
  • Targets Akt, eNOS, TRB3, and PPAR-gamma pathways to limit muscle loss
  • Improvies nutritent partitioning to send calories to muscle not fat and increasing lipolysis
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Why

When dieting your body goes into survival mode sacrificing muscle tissue the leaner you get with multiple pathways causing this muscle loss. Hydra Head Six addresses six distinct pathways to combat this muscle loss via an innovative array of ingredients that work together to increase muscle gain and limit catabolic or muscle wasting actions. The first true anti-catabolic supplement, Hydra Head Six is a potent weapon that inhibits cortisol, promotes satellite cell hypertrophy, improves nutrient partitioning and much, much more.

When

Hydra Head Six will be of most benefit to those who are dieting as it will have a muscle sparing effect while simultaneously increasing the amount of fat you burn. It can also be used productively on a lean bulk to ensure that you minimise the potential for fat gain when bulking.

Who

A natural product which can be taken by anyone but will be of particular benefit to dieters especially those seeking to hit very low levels of bodyfat as that is when the body's propensity to burn muscle off is enhanced and Hydra Head Six can combat this.

Predator Nutrition Hydra Head Six Review

We've spoken frequently about how nobody does innovation like Antaeus Labs and Hydra Head Six is yet again a supplement which defies categorisation being the first true anti-catabolic.

Catabolism Defined

Muscle is continually gained and lost throughout not just a week or a month but within each hour of the day. Whether you end up with more or less muscle at the end of the day is down to the balance between anabolic (muscle building) and catabolic (muscle wasting) factors. The supplement industry has a whole host of products designed to increase anabolism such as proteins, creatine, various natural anabolics, testosterone boosters and so on. However, these only pay attention to the rate at which muscle is built. If your body breaks down muscle too quickly due to catabolism then you end up back to square one. This is where Hydra Head Six comes in - to limit muscles being broken down and thereby increase your net nitrogen balance so that you gain muscle.

A Six-Headed Beast

Fans of Greek mythology will recognise that the Hydra was a fearsome serpent with six heads which could not be killed if only one head was attacked, instead all six had to be decapitated. When it comes to preserving muscle the same scenario plays out. There is little gain from focusing on one cause of muscle loss if other pathways remain that cause you to lose muscle anyway. This is why Hydra Head Six targets six unique pathways in aiming to prevent muscle loss when dieting.

The First Head
The most tantalizing way to decrease catabolism and muscle loss is to directly increase anabolism. Vitamin C 2-phosphate (VC2P) does exactly that. You will see that name, again -- and for good reason. It’s badass. This is not the Vitamin C that was in the orange juice your mom made you for breakfast this morning. VC2P is a much more stable, long acting derivative of regular Vitamin C. More importantly, it is the only form of Vitamin C that can accmulate in muscle cells following oral supplementation. It has been shown to promote both skeletal muscle fiber hypertrophy and differentiation.

Ursolic acid is a triterpenoid found in numerous plants. It has long been demonstrated in the data to have a myriad of beneficial effects, but it normally has poor bioavailability. HH6 complexes it in a cyclodextrin for superior solubility, thus partitioning, thus bioavailability. It potentiates amino acid (leucine) induced muscle differentiation. Further, it has been shown to increase muscle mass, fiber size (both slow and fast twitch), as well as exercise capacity and grip strength. Lastly, Ursolic Acid produced an increase in serum irisin levels and muscle strength -- a fact which may underlie the recomposition effects that users of high-dose ursolic acid products have noted.

The Second Head
Dieting is stress. With a sustained decrease in calories, the body thinks it is starving. This sets off a cascade of metabolic events designed to reduce calorie hungry muscle mass in order to decrease energy expenditure.One of these mechanisms is through increasing cortisol/glucocorticoid activity. Prolonged, excess activation of the glucocorticoid axis is profoundly catabolic.

Our most trusted weapon, VC2P potently inhibits hydrocortisone induced cellular damage. Magnolol, a neolignan from magnolia, also blunts the glucocorticoid cascade via its GABA-A inhibitory activity.

The Third Head
Catabolism is also made widely manifest through the runaway production of reactive oxygen species and inflammation. As with cortisol, it is a normal and necessary part of cellular processes, but like other people’s daughters on spring break, it is bad news when they run wild. VC2P is not only longer acting than Vitamin C, it is a more potent free radical scavenger. Magnolol attenuates inflammation and damage with its own antioxidant activity. Oenothera odorata is a perennial plant from South America. Oenothera odorata root extract suppresses expression of peroxide and superoxide dismutase, reducing muscle atrophy compared to control.

The Fourth Head
Our next pathway is one that you might not typically tend to think of – blood flow. Dieting and weight loss cause vasoconstriction via alpha adrenergic receptor upregulation and increased activity signalling. This decreases the uptake of pro-anabolic nutrients to the muscle cell, as well as decreasing the clearance of catabolic byproducts of metabolism. Ligustrazine is a component of the widely popular Chinese herb, Chuanxiong, which has been found to possess vasorelaxant properties. It induces this vasodilation through an increase in nitric oxide and cGMP. This is the same mechanism as the boner pills, in case you were wondering. (And we know you were)

Magnolol comes to the aid in this fight from the opposite direction. It inhibits vascular contractions through a number of alternate cellular signaling pathways like Akt, eNOS, TRB3, and PPAR-gamma.

The Fifth Head
Malificent nutrient partitioning is yet another way your body gets you, proving its hatred of the strong and beautiful. Basically, nutrients and calories go preferentially to the formation, growth, and maintenance of adipose tissue instead of muscle. Quite obviously, we want to remedy and reverse this – and we are. Increasing the use of adipose tissue as fuel spares muscle mass, and it increases glucose uptake in muscle vs. fat. This increases protein synthesis while also increasing lipolysis, in a virtuous circle.

VC2P positively impacts lipid metabolism by decreasing lipogenesis and increasing lipolysis. Magnolol stimulates glucose uptake in muscle cells by increasing GLUT4 at the cell surface. Further, it activates key protein synthetic elements of the insulin signaling pathway, including mTor and Akt, as well as lipid oxidation pathways like AMPK and PGC-1a.

Ursolic acid acts as an insulin mimetic, increasing GLUT4, glucose uptake, as well as glycogen content of muscle. Even better, it increases brown fat in skeletal muscle, thus increasing thermogenesis, fatty acid oxidation, and energy expenditure.

Ligustrazine increases mitochondrial biogenesis, thus increasing fatty acid utilization. This not only increases fat burning (and may improve insulin related health issues), it spares glucose for use in muscle cells, to preserve energy and mass.

The Sixth Head
Our final and most important tactic in our fight is to directly decrease catabolism itself. That is what this product is for, after all. When dieting, you have to work out less, or you are going to get crushed by overtraining and free radicals and inflammation looting and burning your muscle stores. This decrease in muscle fiber overload is essentially like a mini-version of being bed-ridden. The literature on denervation, hind-leg/tail suspension, immobility, and cold muscle tissue covers this aspect of metabolism, extensively.

Ligustrazine postpones muscle atrophy indenervated muscle by reducing the expression of a number of catabolic enzymes (26). It has likewise been found to do so in tail suspension (simulating weightlessness), with a reduction in atrophy.

One of the most important mechanisms for muscle fiber damage and destruction is an imbalance of intracellular calcium ions. Ligustrazine protects against Ca2+ overload, protecting the muscle mitochondria and the cell. This protection has been found to protect against protein degradation and muscle loss. Our trusted brother in arms, VCP2, releases ascorbate in the muscle cell to protect against this calcium ion excess. It also facilitates the action of IGF-1 on muscle cell formation in cold muscle tissue.

Ursolic acid produces hundreds of small changes in mRNA of muscle cell to combat muscle atrophy and weakness. This is mediated by a protein called ATF4, which is increased with glucose deprivation in the muscle cell. Magnolol suppresses catabolic proteins (including myostatin) and induces protein synthetic agents IGF-1 and Akt, mitigating inflammation and atrophy. Oenothera odorata root extract reduced or fully inhibited several catabolic indicators in denervated muscle, supporting maintenance of muscle mass, strength, and volume.

Flawless Victory. You have done the work, continue to reap the rewards. Hydra Head Six is an absolutely essential instrument in your battle to crush your enemies, see them driven before you, and to hear the lamentations of their women.

Be the first to review this product Write a Review
Hydra Head Six 120 Capsules
Predator Review
Predator Nutrition Hydra Head Six Review

We've spoken frequently about how nobody does innovation like Antaeus Labs and Hydra Head Six is yet again a supplement which defies categorisation being the first true anti-catabolic.

Catabolism Defined

Muscle is continually gained and lost throughout not just a week or a month but within each hour of the day. Whether you end up with more or less muscle at the end of the day is down to the balance between anabolic (muscle building) and catabolic (muscle wasting) factors. The supplement industry has a whole host of products designed to increase anabolism such as proteins, creatine, various natural anabolics, testosterone boosters and so on. However, these only pay attention to the rate at which muscle is built. If your body breaks down muscle too quickly due to catabolism then you end up back to square one. This is where Hydra Head Six comes in - to limit muscles being broken down and thereby increase your net nitrogen balance so that you gain muscle.

A Six-Headed Beast

Fans of Greek mythology will recognise that the Hydra was a fearsome serpent with six heads which could not be killed if only one head was attacked, instead all six had to be decapitated. When it comes to preserving muscle the same scenario plays out. There is little gain from focusing on one cause of muscle loss if other pathways remain that cause you to lose muscle anyway. This is why Hydra Head Six targets six unique pathways in aiming to prevent muscle loss when dieting.

The First Head
The most tantalizing way to decrease catabolism and muscle loss is to directly increase anabolism. Vitamin C 2-phosphate (VC2P) does exactly that. You will see that name, again -- and for good reason. It’s badass. This is not the Vitamin C that was in the orange juice your mom made you for breakfast this morning. VC2P is a much more stable, long acting derivative of regular Vitamin C. More importantly, it is the only form of Vitamin C that can accmulate in muscle cells following oral supplementation. It has been shown to promote both skeletal muscle fiber hypertrophy and differentiation.

Ursolic acid is a triterpenoid found in numerous plants. It has long been demonstrated in the data to have a myriad of beneficial effects, but it normally has poor bioavailability. HH6 complexes it in a cyclodextrin for superior solubility, thus partitioning, thus bioavailability. It potentiates amino acid (leucine) induced muscle differentiation. Further, it has been shown to increase muscle mass, fiber size (both slow and fast twitch), as well as exercise capacity and grip strength. Lastly, Ursolic Acid produced an increase in serum irisin levels and muscle strength -- a fact which may underlie the recomposition effects that users of high-dose ursolic acid products have noted.

The Second Head
Dieting is stress. With a sustained decrease in calories, the body thinks it is starving. This sets off a cascade of metabolic events designed to reduce calorie hungry muscle mass in order to decrease energy expenditure.One of these mechanisms is through increasing cortisol/glucocorticoid activity. Prolonged, excess activation of the glucocorticoid axis is profoundly catabolic.

Our most trusted weapon, VC2P potently inhibits hydrocortisone induced cellular damage. Magnolol, a neolignan from magnolia, also blunts the glucocorticoid cascade via its GABA-A inhibitory activity.

The Third Head
Catabolism is also made widely manifest through the runaway production of reactive oxygen species and inflammation. As with cortisol, it is a normal and necessary part of cellular processes, but like other people’s daughters on spring break, it is bad news when they run wild. VC2P is not only longer acting than Vitamin C, it is a more potent free radical scavenger. Magnolol attenuates inflammation and damage with its own antioxidant activity. Oenothera odorata is a perennial plant from South America. Oenothera odorata root extract suppresses expression of peroxide and superoxide dismutase, reducing muscle atrophy compared to control.

The Fourth Head
Our next pathway is one that you might not typically tend to think of – blood flow. Dieting and weight loss cause vasoconstriction via alpha adrenergic receptor upregulation and increased activity signalling. This decreases the uptake of pro-anabolic nutrients to the muscle cell, as well as decreasing the clearance of catabolic byproducts of metabolism. Ligustrazine is a component of the widely popular Chinese herb, Chuanxiong, which has been found to possess vasorelaxant properties. It induces this vasodilation through an increase in nitric oxide and cGMP. This is the same mechanism as the boner pills, in case you were wondering. (And we know you were)

Magnolol comes to the aid in this fight from the opposite direction. It inhibits vascular contractions through a number of alternate cellular signaling pathways like Akt, eNOS, TRB3, and PPAR-gamma.

The Fifth Head
Malificent nutrient partitioning is yet another way your body gets you, proving its hatred of the strong and beautiful. Basically, nutrients and calories go preferentially to the formation, growth, and maintenance of adipose tissue instead of muscle. Quite obviously, we want to remedy and reverse this – and we are. Increasing the use of adipose tissue as fuel spares muscle mass, and it increases glucose uptake in muscle vs. fat. This increases protein synthesis while also increasing lipolysis, in a virtuous circle.

VC2P positively impacts lipid metabolism by decreasing lipogenesis and increasing lipolysis. Magnolol stimulates glucose uptake in muscle cells by increasing GLUT4 at the cell surface. Further, it activates key protein synthetic elements of the insulin signaling pathway, including mTor and Akt, as well as lipid oxidation pathways like AMPK and PGC-1a.

Ursolic acid acts as an insulin mimetic, increasing GLUT4, glucose uptake, as well as glycogen content of muscle. Even better, it increases brown fat in skeletal muscle, thus increasing thermogenesis, fatty acid oxidation, and energy expenditure.

Ligustrazine increases mitochondrial biogenesis, thus increasing fatty acid utilization. This not only increases fat burning (and may improve insulin related health issues), it spares glucose for use in muscle cells, to preserve energy and mass.

The Sixth Head
Our final and most important tactic in our fight is to directly decrease catabolism itself. That is what this product is for, after all. When dieting, you have to work out less, or you are going to get crushed by overtraining and free radicals and inflammation looting and burning your muscle stores. This decrease in muscle fiber overload is essentially like a mini-version of being bed-ridden. The literature on denervation, hind-leg/tail suspension, immobility, and cold muscle tissue covers this aspect of metabolism, extensively.

Ligustrazine postpones muscle atrophy indenervated muscle by reducing the expression of a number of catabolic enzymes (26). It has likewise been found to do so in tail suspension (simulating weightlessness), with a reduction in atrophy.

One of the most important mechanisms for muscle fiber damage and destruction is an imbalance of intracellular calcium ions. Ligustrazine protects against Ca2+ overload, protecting the muscle mitochondria and the cell. This protection has been found to protect against protein degradation and muscle loss. Our trusted brother in arms, VCP2, releases ascorbate in the muscle cell to protect against this calcium ion excess. It also facilitates the action of IGF-1 on muscle cell formation in cold muscle tissue.

Ursolic acid produces hundreds of small changes in mRNA of muscle cell to combat muscle atrophy and weakness. This is mediated by a protein called ATF4, which is increased with glucose deprivation in the muscle cell. Magnolol suppresses catabolic proteins (including myostatin) and induces protein synthetic agents IGF-1 and Akt, mitigating inflammation and atrophy. Oenothera odorata root extract reduced or fully inhibited several catabolic indicators in denervated muscle, supporting maintenance of muscle mass, strength, and volume.

Flawless Victory. You have done the work, continue to reap the rewards. Hydra Head Six is an absolutely essential instrument in your battle to crush your enemies, see them driven before you, and to hear the lamentations of their women.

Customer Reviews
Be the first to review this product Write a Review
Nutrition

Nutrition

Antaeus Labs Hydra Head Six - 120 capsules
Serving size: 1 capsule
Serving per container: 120
  Amount Per Serving %DV**
Ascorbic acid 2-phosphate 250mg *
Ursolic acid cyclodextrin complex 125mg *
Oenothera Ordorate root extract 20:1 75mg 250%
Ligustrazine 50mg *
Magnolol 50mg *
* Daily value not established    
Other ingredients: Gelatin, Silicon dioxide, microcrystalline cellulose
Directions For Use
As a dietary supplement, take two capsules twice daily. Do not take over eight capsules per day. Take with meals.

Nutrition

Antaeus Labs Hydra Head Six - 120 capsules
Serving size: 1 capsule
Serving per container: 120
  Amount Per Serving %DV**
Ascorbic acid 2-phosphate 250mg *
Ursolic acid cyclodextrin complex 125mg *
Oenothera Ordorate root extract 20:1 75mg 250%
Ligustrazine 50mg *
Magnolol 50mg *
* Daily value not established    
Other ingredients: Gelatin, Silicon dioxide, microcrystalline cellulose

Antaeus labs: Hydra Head Six

Directions For Use
As a dietary supplement, take two capsules twice daily. Do not take over eight capsules per day. Take with meals.