Evomuse : Clear Edge Nootropic

Clear Edge by Evomuse is a highly rated nootropic supplement that gives you an edge in mental performance. It contains an endless amount of ergogenic aids that help to improve brain output efficiency resulting in an increase in reaction and thought processing, improve memory formation and accelerate learning and improve your ability to recall information.

This supplement is relevant to everyone looking for a psychological ergogenic aid to get them in the zone. It’s beneficial for the avid gamer, the successful entrepreneur or for the elite athlete where fine margins can make all the difference between success and failure. If you are in a situation where you need to be at the top of your game mentally or just need that psychological edge on a daily basis, then this supplement is for you.

There is a great number of effective ingredients in Clear Edge, so only the five core ingredients have been reviewed below.

Bacopa Monnieri

This herb belongs to the plant family Scrophulariaceae and is commonly referred to as brahmi. It is found in India and the neighbouring tropical countries. There have been a number of studies conducted on this herb looking at its ability to augment learning, language and memory. Studies have displayed bacopa monnieri to display significant improvements in total memory, logical memory, paired associate learning and language behaviour. One study found it to improve mental speed by 31.7% and logical memory by 52.9%. Many studies have also shown it to be able to shield neuronal structure and function.

How It Works

Bacopa monnieri ability to provide neuroprotective and memory enhancing effects work through many mechanisms. It’s primary influence on being able to protect the brain against oxidative damage as it’s an antioxidant is only the beginning of its benefits. Its neuroprotective effects work through its ability to increase nitric oxide-mediated cerebral vasodilation. It can also bind and detoxify metal ions, promote free radical scavenger mechansims, reduce lipoxygenase activity and increases gluathione peroxidase activity. Bacopa monnieri is also lipophilic. This means it can dissolve in lipids, allowing it to cross the blood-brain barrier and repair damaged neurons by increasing kinase activity linked with the restoration of synaptic activity- resulting in an improvement of nerve impulse transmission.

Nelumbo Nucifera Extract

This is an aquatic herb that belongs to the Nymphaeaceae family and is commonly consumed throughout Asia. It’s use in Ayurveda, Chinese and oriental medicine has been used for a wide range of illnesses such as tissue inflammation, cancer, diabetes, skin diseases and cardiovascular diseases. It’s high antioxidant content means it has the ability to possess high levels of free radical scavenging activity and nitric oxide scavenging activity- even greater levels than the popular flavonoid rutin.

Huperzine A

This is a firmoss that is derived from Huperzia Serrata, that has been used in traditional Chinese medicine for fever and inflammation. It’s recent use has been used for neurological disorders such as alzheimer’s disease and dementia and how it can provide a neuroprotective effect on these types of conditions.

How It Works

It’s suggested mechanism involves its action via central nicotinic and muscarinic receptors. As it produces a potent anti-inflammatory response, this effect provides protection from excitotoxicity and neuronal death.

Ginko Biloba

This herb is also a highly researched and prominent when looking at neurological conditions such as dementia and Alzheimer’s disease. A recent review of all the studies conducted on ginko biloba in over 2500 participants displayed it to display improvements in overall cognition and activities of daily living at a dose of 240mg per day.

How It Works

The proposed mechanism of action for ginko biloba include its effects on preserving and improving mitochondrial function, promote hippocampal neurogenesis and neuroplasticity and enhance cerebral blood flow.

L-DOPA

L-DOPA is an ingredient that is becoming very popular and receiving a great deal of attention due to it being able to be transformed into dopamine and released from 5-HT terminals, resulting in an impact on 5-HT neurotransmission. L-DOPA can also be taken up by all of the cells in the brain.

How It Works

Studies have shown L-DOPA to be able to modify the activity of 5-HT neurons and increase the dorsal raphe nucleus activity and subsequently increase the dorsal raphe nucleus activity neuron firing rate. The proposed mechanism of L-DOPA working suggests its ability to influence 5-HT neurons- primarily on its effect on 5-HT biosynthesis and on 5-HT transporter level and neuron survival.