Hydrapharm : Ether Nitric Oxide Supplement

Hydrazine’s powerful stimulant and nootropic pre-workout Hydrazine has been one of our bestselling supplements across ALL categories for many years now. If we were to be super picky, the only thing that the product was possibly lacking to make it complete when using before a training session was a ‘pump’ element. Hydrapharm have heard us and answered our prayers!

At long last, we have the pump and bloodflow product we’ve all been waiting for. Like all Hydrapharm products, the formula is completely unique to them. A combination of ingredients we’ve never seen before, a refreshing change from the dozens of copycat non-stims on the market.

In each serving, you’ll find 4 ingredients, all of which offer something special to Ether. Hydrapharm’s R&D department spent YEARS experimenting with the ratios of each and making small tweaks until they were left with the perfect final product. Not a single part of the process was rushed for the sake of having a stim-free product to offer fans of the brand. Remember, it’s not just the ingredients and dosages used in a product that matter. It’s how each ingredient compliments the next. You can read all about the backstory in our Ether Review.

The Formula

In 2021, it's not enough to just throw a few 'good' ingredients together. It's all been done before! As ever, Hydrapharm's R&D team are leagues ahead of the competition. In this product, they introduce world first ingredient Aminoethlyl Nitrate (AEN). AEN is a nirate 100x more powerful than other nitric oxide boosters on the market! Through causing the dilation of blood vessels, it allows blood to flow to working muscles and around the body more easily. Pumps, waste removal, vascularity, reduced blood pressure, endurance... the list of potential benefits this offers are near endless! This potent nitrate is one we expect to see other brands follow suit with in coming years!⁽⁵⁾ Nitrates administered pre-workout can have ergogenic impacts on athletic performance in endurance athletes.⁽⁶⁾

Probably most known and understood ingredient is L-Citrulline. Through the L-arginine/nitric oxide pathway, L-Citrulline has been shown to enhance exercise performance in healthy adults, as well as leading to a reduction in blood pressure, something which many larger bodybuilders may suffer with.⁽¹⁾ Citrulline also has positive effect on the rate of perceived exertion and muscular pain as well as reducing muscular lactate.⁽²⁾ These benefits make citrulline excellent for muscular endurance and bloodflow during training as well as improved health markers.

Next up, is Inositol Arginine Silicate. In rat studies, arginine silicate inositol complex is absorbed efficiently, raising plasma arginine levels. An important precursor to nitric oxide, which offers benefit to exercise and cardiovascular health.⁽³⁾

Glycine Propionyl-l-Carnitine is another phenomenal ingredient which, like many that Hydrapharm use, is a superior version of standard ingredients used by other brands. Glycine propionyl-L-carnitine (GPLC) is a propionyl ester of carnitine that includes an additional glycine component. In the body, it converts to glycine, carnitine and propionic acid. When combined with resistance training, GPLC has been shown to increase nitric oxide levels.⁽⁴⁾

Stacking

This can be used any time, or stacked with Hydrazine for your most intense and mentally demanding sessions.

References

(1) Figueroa, A., Wong, A., Jaime, S. and Gonzales, J., 2017. Influence of L-citrulline and watermelon supplementation on vascular function and exercise performance. Current Opinion in Clinical Nutrition & Metabolic Care, 20(1), pp.92-98.

(2) Huerta Ojeda, Á., Domínguez de Hanna, A. and Barahona-Fuentes, G., 2019. The effect of supplementation with L-arginine and L-citrulline on physical performance: a systematic review. Nutrición Hospitalaria,.

(3) Proctor, S., Kelly, S., Vine, D. and Russell, J., 2007. Metabolic effects of a novel silicate inositol complex of the nitric oxide precursor arginine in the obese insulin-resistant JCR:LA-cp rat. Metabolism, 56(10), pp.1318-1325.

(4) Bloomer, R., Tschume, L. and Smith, W., 2009. Glycine Propionyl-L-carnitine Modulates Lipid Peroxidation and Nitric Oxide in Human Subjects. International Journal for Vitamin and Nutrition Research, 79(3), pp.131-141.

(5) Bauersachs, J., 2009. Aminoethyl nitrate - the novel super nitrate?. British Journal of Pharmacology, 158(2), pp.507-509.

(6) Lorenzo Calvo, J., Alorda-Capo, F., Pareja-Galeano, H. and Jiménez, S., 2020. Influence of Nitrate Supplementation on Endurance Cyclic Sports Performance: A Systematic Review. Nutrients, 12(6), p.1796.