Predator Nutrition : Amentoflavone Natural Performance Enhancer

Amentoflavone is the latest product added to the Predator Nutrition range of premium supplements. Amentoflavone is a common biflavonoid that is naturally present in many plants and has been used as traditional folk medicine across the world for thousands of years. Amentoflavone is beneficial to active individuals as it helps with muscular strength, aids weight loss and increases vasodilation. Increasing vasodilation allows the body to bring oxygen into the cells to help meet the demands of intense exercise. Where amentoflavone really excels is the benefits it can provide to improve general health.

Strength Benefits

Amentoflavone exhibits the ability to boost strength by increasing calcium ion concentration for stronger muscle contractions and enhances capillarization and nutrient delivery for greater muscle endurance. The increase in muscular calcium concentration is similar to caffeine’s’ ability to activate this as well, but amentoflavone is 20 times more potent than caffeine.

Fat Loss

The role of amentoflavone in weight loss is well researched. One study researched the protective effects of amentoflavone on fat cells. It was shown to provide a protective effect against a high fat diet induced metabolic dysfunction by decreasing fasting blood glucose levels and fasting insulin levels. The study also found that amentoflavone significantly inhibited an increase in body weight and the weight of adipose tissue.

Health Benefits

The study of amentoflavone in modern pharmacology has displayed it’s bioactivities to include: anti-oxidant, anti-inflammatory, anti-hyperlipidemia, anti-senescence, anti-tumour, anti-virus, anti-fungal effects, as well as providing therapeutic effects on the central nervous system and cardiovascular system.

Anti-Oxidant and Anti-Inflammation Properties

Amentoflavone has been found in over 120 plants with varying content. Amentoflavone has displayed anti-oxidant and anti-inflammatory properties in studies through it’s ability to inhibit the effects of the production of total reactive oxygen species, supress the production of prostaglandin E-2 and extracellular signal-regulated kinase.

The use of amentoflavone is currently being advocated for pharmacological purposes, but there is the issue of being able to extract a sufficient amount as some plants may only contain 0.1% of this wonder ingredient. It has been suggested that in the future we may need to find plants with a much higher content of amentoflavone or even chemically synthesize it.

Anti-Senescence

Amentoflavone has also shown to prevent skin photoaging. Ultraviolet irradiation has shown to increase the levels of Lamin A and phospho-H2AX protein in normal human fibroblasts. These are common markers that are present in premature aging diseases. Amentoflavone was able to ameliorate these damages and protect nuclear aberration significantly.

Anti-Diabetes

Amentoflavone provides a host of benefits in combatting diabetes. It’s been observed that it can provide benefits to glucose disorders, help regulate insulin secretion and restore pancreatic function. It has also shown to act against protein tyrosine phosphatase 1B, which the inhibition of is being considered as a strategy to treat type 2 diabetes.

Benefits to the Central Nervous System and Cardiovascular System

The effects amentoflavone has on the central nervous system surrounds its wide-ranging benefits to psychological health. It has shown to provide attenuate depression caused by metergoline (5-HT2 receptor antagonist), prazosin (α1-adrenoceptor antagonist), or yohimbine (α2-adrenoceptor antagonist). It has also shown to improve anxiety stimulated by flumazenil (ionotropic GABA receptor antagonist). Amentoflavone has displayed antidepressant effects with interacting with the receptors above and providing beneficial outcomes.

Amentoflavones beneficial effects for cardiovascular health come from its ability to enhance vasodilation. It can help to enhance myocardial contraction, expand peripheral vessels, and improve hemodynamics of heart failure patients.