Fadogia Agrestis: Uses, Benefits, Dosage & Side Effects

Fadogia Agrestis, an herb native to West Africa, is mainly known for its potential benefits in hormonal health, athletic performance, and overall well-being. In the past few years more people have turned to natural solutions to support their health goals, which is why in this article we will look at what Fadogia Agrestis is, how it works, and what the science says about its efficacy and safety. More specifically, we will delve into its origins, traditional uses, and why it has spiked recent interest. You'll also learn about its potential benefits, recommended dosages, and possible side effects, helping you make an informed decision about whether this supplement is right for you.

What is Fadogia Agrestis?

Fadogia Agrestis, also known as Bakin Gagai, is a small shrub belonging to the Rubiaceae family. Native to West African countries such as Nigeria, Ghana, and Mali, this plant has been used for centuries in traditional medicine for its purported aphrodisiac and stimulant properties [1].

The stem and roots of Fadogia Agrestis contain several bioactive compounds, including alkaloids, saponins, and flavonoids, which are believed to be responsible for its medicinal effects [2]. Traditionally, the plant has been used to treat various ailments, such as malaria, erectile dysfunction, and low libido [1].

Benefits of Fadogia Agrestis

1) Hormonal Health
One of the most notable benefits of Fadogia Agrestis is its potential to support hormonal health, particularly in men. Research suggests that this herb may help increase testosterone levels, a crucial hormone for male sexual function, muscle growth, and overall well-being. A study conducted on male rats found that oral administration of Fadogia Agrestis extract significantly increased serum testosterone levels compared to the control group [1].

2) Athletic Performance
Fadogia Agrestis may also hold promise for improving athletic performance. Testosterone plays a vital role in muscle growth and recovery, and by potentially increasing testosterone levels, this herb may support these processes. Furthermore, the potential anti-inflammatory and antioxidant properties of Fadogia Agrestis may aid in post-exercise recovery. Inflammation and oxidative stress are common after intense workouts, and reducing these factors can help minimise muscle damage and soreness.

3) General Wellness
In addition to its specific benefits for hormonal health and athletic performance, Fadogia Agrestis may contribute to overall well-being. Its potential anti-inflammatory and antioxidant effects could help combat oxidative stress, which is linked to various chronic diseases and ageing processes. By reducing inflammation and neutralising harmful free radicals, this herb may support cellular health and longevity.

Moreover, some users report improved energy levels and mood when taking Fadogia Agrestis supplements. While more research is needed to confirm these effects, the potential testosterone-boosting properties of this herb may play a role in enhancing vitality and overall sense of well-being.

Scientific Studies

A study conducted on rodents revealed that supplementing with Fadogia agrestis for just five days led to impressive increases in testosterone levels, with the effects being dose-dependent. Testosterone levels increased by 2-fold, 3-fold, and 6-fold when the rodents were given 18 mg/kg, 50 mg/kg, and 100 mg/kg of Fadogia agrestis, respectively. Additionally, the herb enhanced libido in the rodents [3]. 

Compared to other herbs known for their testosterone-boosting and libido-enhancing properties, such as Spilanthes acmella, Fadogia agrestis appears to be one of the most potent options, demonstrating greater effect sizes [3][4]. Another study performed on rodents found that supplementing with Fadogia agrestis led to an increase in testicular weight, ranging from 11% to 15% [5].

While there is limited animal research supporting the pro-erectile effects of Fadogia agrestis, an interesting observation has been made regarding its impact on ejaculation latency, which refers to the time it takes to reach ejaculation. Unlike most aphrodisiacs that typically reduce ejaculation latency, Fadogia agrestis has been noted to increase it, making it a unique herb in this regard [3].

Beyond its aphrodisiac properties, Fadogia agrestis has shown promise in other areas as well. An in vitro study isolated glycosides from the roots of Fadogia agrestis and discovered that some of these compounds exhibited inhibitory effects against certain parasites and bacteria. Moreover, they demonstrated mild antimalarial activity [6]. Another in vitro study revealed that Fadogia agrestis possessed antispasmodic properties, suggesting its potential use in managing conditions related to muscle spasms [7].

Recommended Dosage of Fadogia Agrestis

General Guidelines
Currently, there are no official dosage guidelines for Fadogia Agrestis, as research on its optimal dosage in humans is limited. However, most commercial supplements contain a daily dose ranging from 300 mg to 1,200 mg of Fadogia Agrestis extract, usually divided into two or three servings.

It is crucial to follow the manufacturer's recommended dosage on the product label, as the concentration of active compounds may vary between different brands and formulations. The best approach is to start with a lower dose and gradually increase it while monitoring your body's response.

Factors Influencing Dosage
Several factors can influence the appropriate dosage of Fadogia Agrestis for an individual. Age, weight, and overall health status should be considered when determining the optimal dose. For example, older individuals or those with pre-existing health conditions may require lower doses to minimize the risk of adverse effects.

Moreover, the specific health goals one aims to achieve with Fadogia Agrestis supplementation can impact the dosage. Those seeking to enhance muscle gain and athletic performance may require higher doses compared to individuals primarily interested in supporting their libido and sexual function.

Potential Side Effects and Risks

While Fadogia Agrestis is generally well-tolerated, some users may experience mild to moderate side effects. The most common adverse reactions reported include gastrointestinal discomfort, such as nausea, bloating, and diarrhoea. These side effects are typically temporary and subside as the body adapts to the supplement. Some individuals may also experience headaches, dizziness, or restlessness, particularly when taking higher doses.

One potential concern with Fadogia Agrestis is its long-term safety. As research on this herb is still limited, the potential risks associated with prolonged use are not fully understood. Some experts suggest that chronic use of testosterone-boosting supplements, including Fadogia Agrestis, may lead to hormonal imbalances or adverse effects on the liver and kidneys. 

Fadogia Agrestis may also interact with certain medications and other supplements. Its potential effects on testosterone levels could interfere with hormone replacement therapy or other hormone-related treatments.

Pregnant and breastfeeding women should avoid using Fadogia Agrestis due to the lack of safety data in these populations. Individuals with pre-existing health conditions, particularly those related to hormonal imbalances or liver and kidney function, should consult their healthcare provider before starting supplementation.

Where can I buy Fadogia Agrestis

While there is a wide range of brands offering a variety of products containing Fadogia Agrestis, we are somewhat biased towards a few, due their quality and overall ingredients list. The first product we recommend is Predator Nutrition’s Test Elite, not because it’s our product, but because it is an extremely well-rounded test booster containing a whopping 1200mg of Fadogia Agrestis alongside another 16 vital ingredients for boosting and keeping your levels high in a natural way. 

For a product with a shorter ingredients list, but equal amount of Fadogia, you can check M-Test by Competitive Edge Labs which is a great natural muscle builder with clinically dosed ingredients. With that being said, if Fadogia Agrestis is all you are after, then the third and final product we can recommend checking out is Fadogia XT by Serious Nutrition Solutions , which is a budget-friendly option containing 625mg of the ingredient. 

All the three products are great and it all comes down to your personal preference and overall goal. If you’ve just finished your prohormone cycle then a well-rounded product like Test Elite will be a much more suitable option, while if you just want to dip your toes in the water and see how your body reacts to Fadogia, then a standalone product might be better suited for you. 

Conclusion

Fadogia Agrestis is an intriguing herb that has gained popularity for its potential benefits in hormonal health, athletic performance, and overall well-being. Its traditional use as an aphrodisiac and the growing body of scientific research supporting its effects on testosterone levels and sexual function have made it an attractive option for those seeking natural alternatives to conventional treatments.

For individuals who decide to incorporate Fadogia Agrestis into their wellness routine, it is essential to follow the recommended dosage guidelines and monitor their body's response. Starting with a lower dose and gradually increasing it, as well as cycling the supplement, may help minimise the risk of adverse effects and maintain its efficacy over time.

FAQs

How to take Fadogia Agrestis?
Fadogia Agrestis supplements are typically taken orally, either as capsules or tablets. It is generally recommended to take the supplement with meals to enhance absorption and reduce the risk of gastrointestinal discomfort. Dividing the daily dose into two or three smaller servings throughout the day may help maintain stable levels of the active compounds in the body.

It is essential to consult with a healthcare professional before starting any new supplement regimen, including Fadogia Agrestis. They can provide personalised guidance on the appropriate dosage based on your individual needs, health status, and potential interactions with other medications or supplements.

What are the key benefits of taking Fadogia Agrestis supplements?
Some of the key benefits associated with taking Fadogia Agrestis supplements include improved libido, increased sexual performance, and enhanced overall sexual health. Additionally, some studies suggest that Fadogia Agrestis may have potential benefits for prostate health and may help alleviate symptoms of benign prostatic hyperplasia (BPH).

Does Fadogia Agrestis increase testosterone?
While some preliminary studies have suggested that Fadogia Agrestis may have a positive effect on testosterone levels, more research is needed to confirm these findings. A study conducted on male rats found that Fadogia Agrestis extract increased testosterone levels and improved sexual behaviour[1]. However, it is important to note that the results from animal studies may not directly translate to humans, and more human clinical trials are necessary to establish the effectiveness of Fadogia Agrestis in increasing testosterone levels.

Is Fadogia Agrestis Better Than Tongkat Ali?
Fadogia Agrestis and Tongkat Ali (Eurycoma longifolia) are both herbs that are commonly used for their potential male enhancement properties. While both herbs have shown promise in improving libido and sexual performance, there is limited research directly comparing the effectiveness of these two supplements. Ultimately, the choice between Fadogia Agrestis and Tongkat Ali may depend on individual preferences and specific health goals, and it is always best to consult with a healthcare professional before starting any new supplement regimen.

When should I take Fadogia Agrestis supplements?
The optimal timing for taking Fadogia Agrestis supplements may vary depending on the specific product and individual preferences. Some people prefer to take the supplement in the morning to benefit from its potential energy-boosting effects throughout the day, while others may choose to take it in the evening or before sexual activity to enhance libido and performance. It is generally recommended to take Fadogia Agrestis supplements with meals to improve absorption and reduce the risk of gastrointestinal discomfort. As with any supplement, it is essential to follow the manufacturer's instructions and consult with a healthcare professional to determine the most appropriate timing and dosage for your individual needs.

References

[1] Yakubu, M. T., Akanji, M. A., & Oladiji, A. T. (2005). Aphrodisiac potentials of the aqueous extract of Fadogia agrestis (Schweinf. Ex Hiern) stem in male albino rats. Asian Journal of Andrology, 7(4), 399-404.
[2] Yakubu, M. T., & Akanji, M. A. (2011). Effect of aqueous extract of Massularia acuminata stem on sexual behaviour of male Wistar rats. Evidence-Based Complementary and Alternative Medicine, 2011, 738103.
[3] Yakubu MT, Akanji MA, Oladiji AT Aphrodisiac potentials of the aqueous extract of Fadogia agrestis (Schweinf. Ex Hiern) stem in male albino rats.Asian J Androl.(2005-Dec)
[4] Vikas Sharma, Jente Boonen, Nagendra S Chauhan, Mayank Thakur, Bart De Spiegeleer, V K Dixit. Spilanthes acmella ethanolic flower extract: LC-MS alkylamide profiling and its effects on sexual behavior in male ratsPhytomedicine.(2011 Oct 15)
[5] Yakubu MT, Akanji MA, Oladiji AT. Effects of oral administration of aqueous extract of Fadogia agrestis (Schweinf. Ex Hiern) stem on some testicular function indices of male rats.J Ethnopharmacol.(2008-Jan-17)
[6] Osman AG, Ali Z, Fantoukh O, Raman V, Kamdem RST, Khan I. Glycosides of ursane-type triterpenoid, benzophenone, and iridoid from () and their anti-infective activities.Nat Prod Res.(2020-Mar)
[7] Sanon S, Ollivier E, Azas N, Mahiou V, Gasquet M, Ouattara CT, Nebie I, Traore AS, Esposito F, Balansard G, Timon-David P, Fumoux F. Ethnobotanical survey and in vitro antiplasmodial activity of plants used in traditional medicine in Burkina Faso.J Ethnopharmacol.(2003-Jun)