Supplements for Immune Support


Supplements for Immune Support

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Which Supplements are Best for Supporting the Immune System?

Which ingredient has been shown to INHIBIT VIRUSES via strong antiviral activity?


Learn why TESTOSTERONE IS CRUCIAL in immune response

Find out how ANDROSTENEDIOL SUPPORTS IMMUNITY and infectious disease response

Find out why it is NOT THE BEST KNOWN INGREDIENTS that you need most

Which ingredients have ANTI-VIRAL PROPERTIES?



Plus what TRIPLE STACK OF ANTIVIRAL INGREDIENTS is included in two separate Hydrapharm products?

We have spent months studying the research on nutraceutical and hormonal agents to help you make informed decisions:

  • What supplements could help to support immunity
  • Which ones have the best research
  • Which ones to avoid
  • Which have evidence specifically in relation to influenza 
  • What strategies maximise your personal safety during the pandemic
  • And lots lots more

We will also delve into:

  • How being overweight makes you more likely to become sick and more likely to suffer a severe illness
  • The benefits of using hand sanitiser
  • We explore the evidence for an additional five micronutrients in supporting immune function – ashwagandha, cinnamon extract, selenium, n-acetyl cysteine, garlic, spirulina and bee pollen.

Does being overweight weaken the immune system?

While obesity is established as being both immunosuppressive and inflammatory, there has been less attention paid to those who are merely above their optimal level of bodyfat. However, given diseases such as diabetes (another risk factor for contracting multiple illnesses) do not just occur overnight, but instead show a steady progression in time, we explore the potential for insulin resistance, which increases in severity with greater levels of bodyfat, being a potential underlying health condition that makes you more liable to suffer serious complications from other illnesses.

A number of glucose disposal agents have shown tremendous evidence both for managing excess bodyweight and displaying antimicrobial benefits including strong antiviral properties. This is unlikely to be a coincidence but instead suggestive of the fact that there exists a sliding scale with those who are lean at one end, while those who are obese are at the other end. In between those two extremes, will be those who struggle with impaired insulin sensitivity but who are not technically obese – such individuals should prioritise both optimising their insulin sensitivity and losing excess bodyfat.

New Immunity Support Ingredients Reviewed

We now have added in sections on – ashwagandha, cinnamon extract, selenium, n-acetyl cysteine, garlic, spirulina and bee pollen. We will be updating the section on immune supporting nutrients as additional new research comes into focus.

Symptom Management for Seasonal Illnesses 

Those who have fallen ill and are experiencing only mild symptoms are generally advised to rest at home and only to use those medicines which are designed to manage the most common symptoms, namely a fever and a dry cough. Should symptoms persist past a few days, it is advised to seek further medical advice.

Paracetamol (Acetaminophen) – Paracetamol is recommended for the management of pain and for helping control a fever.

Pholcodine – Pholcodine is a medicine which is indicated for the treatment of unproductive coughs or dry coughs.

Codeine Linctus – Codeine is similarly used for the treatment of unproductive coughs. Unlike pholcodine, codeine linctus also has some analgesic properties.


Surgical Grade Sanitiser

While personal hygiene and disinfecting surfaces remains paramount, we can now offer a surgical grade hand sanitiser which is used in hospitals to disinfect the hands of surgeons before they commence operating on patients. Indeed, as a full spectrum antimicrobial spray, it both lasts far longer than a regular hand sanitiser, as well as being more versatile, and effective.

We recommend carrying it with you and using it spray anything which your fingers come into contact with, and it is especially useful for spraying containers of food and to make sure they are virus free. Imagine how many hands a packet of potato chips will have gone through before you open it and consume it – these are the types of situations where a spray of the exterior surfaces ensures you don't transfer the virus from the packaging, onto your fingers and then into your mouth when you put a potato chip in your mouth.

A Review of Supplements Used for Supporting Immunity

There is a huge amount of research that has been conducted into the different supplements which show evidence of being useful in protecting the body from infection, supporting immune function, or even showing antimicrobial properties. For those interested in receiving a pdf book which goes into greater detail than this article permits, you can signup to claim a free copy by entering your email address below. However, this article summarises most of the key findings.

For those more interested in what to take, and how much to take you can use the table below to help guide you but we recommend you read the detailed notes against each nutrient so you can best select the particular supplements that will be most beneficial in your unique case.

Supplements for Supporting Immunity

Name Rating Buy at
Berberine, Oxymatrine, Ecklonia Cava, Cinnamon Blend ***** Buy Elixir Blend
Male Health ***** Buy Male Health
Premium Multivitamin Blend (Incl. Vitamin C, D and E) ***** Buy Premium Vitamin Blend
Salidroside **** Buy Salidroside
BPC-157 **** Buy BPC-157
Echinacea **** Buy Echinacea
Vitamin C **** Buy Vitamin C
Vitamin D **** Buy Vitamin D
Zinc **** Buy Zinc
Ashwagandha **** Buy Ashwagandha
Female Health *** Buy Female Health
Probiotics *** Buy Probiotics
Elderberry *** Buy Elderberry
N-Acetylcysteine ** Buy NAC
Selenium ** Buy Selenium
Garlic ** Buy Garlic
Spirulina * Buy Spirulina
Green Tea * Buy Green Tea
Bee Pollen * Buy Bee Pollen

Note that in grading the nutrients above from 5 stars (most useful) to 1 stars (least useful), we have made a decision based on the numerous factors discussed below including the quality and scope of potential effects, the quality of evidence, and focused on those nutrients shown in research to have antiviral effects or evidence of effectiveness against respiratory tract infections in the research database reviewed.


Berberine – Strong Antimicrobial Action

Berberine is a natural ingredient which has shown anti-influenza activity[14] as well as its anti-inflammatory, and broad antimicrobial action against viruses, fungus, and bacteria. The researchers stated “berberine strongly suppressed viral replication” and relieved symptoms including pulmonary inflammation, a common symptom of respiratory infections.

A separate study on berberine’s effects on viral infections concluded that “Berberine derivatives inhibits various strains of influenza[15] , and it exhibits antiviral effects both in vitro and in vivo with the ability to inhibit virus infection in influenza and improving pathogenic changes by repressing inflammatory substance release[16].

Oxymatrine – Antiviral and Anti-Inflammatory Compound

Oxymatrine has evidence supporting its ability to inhibit influenza replication and reduce inflammation with it being used in clinical settings for years while one study from 2018 showed it exhibits “excellent anti influenza A virus activity”[17] and was able to reduce activity in eight different strains of influenza and “suppress the expressions of inflammatory cytokines”.

Furthermore, oxymatrine showed significant symptomatic improvements with the ability to “significantly increases survival rate, decrease the lung index, pulmonary inflammation andf lung viral tittle, and improve pulmonary histopathological changes.”

Ecklonia Cava – Antimicrobial Activity

Ecklonia Cava – A compound derived from seaweed, ecklonia cava has a number of remarkable properties including not just antiviral but antimicrobial, antioxidant and anticancer properties,[18][19] as well as more recently being investigated as a treatment for the prevention and treatment of influenza infections[20] with it displaying potent inhibitory effects against influenza[21] as well as effects that make it useful for improving body composition, antiviral, protecting liver function and showing anti-inflammatory effects.[22]

Ecklonia Cava and Coronaviruses

Even more interestingly, this study noted the following:

“Given the importance of severe acute respiratory syndrome coronavirus 3C-like proteinase (SARS-CoV 3CLpro) in viral replication, a biological assessment was completed on the phlorotannins isolated from E. cava. In this study, the E. cava phlorotannins were shown to inhibit SARS-CoV3CLpro competitively in cell-free systems."

You can find more information on ecklonia cava’s potential benefits with respect to coranaviruses in a 2013 study that concluded it had “strong antiviral activity… and may be developed into natural therapeutic drugs against coronavirus infection.”[23]

Interestingly enough, the researchers concluded that of all the potential health benefits associated with ecklonia cava extract, the most potential could relate to its anti-carcinogenic effects. We’d recommend reading the full study to learn more.

Furthermore, you may be interested to know that ecklonia cava has shown a number of other antiviral effects against both measles[24] and HIV[25] among other viral infections.

Athletes may be interested to know that numerous studies support its use for combating fat gain and indeed this final benefit is one reason it has become a popular ingredient among athletes.[26][27]

Cinnamon Extract

Traditional Chinese medicine has used cinnamon extracts for the improvement or protection against the common cold[103] while another study showed that it possessed potential antibacterial activity against a wide variety of bacteria including the Haemophilus Influenza[104]. However, rather than its direct effects in combating pathogens, cinnamon's greatest benefits are likely to be indirect, through its role in combating weight gain.

Being overweight is linked to pathogenicity due to excess bodyfat being linked to immunosuppression and greater inflammation. In other words, those who are overweight are more likely to contract an infection and suffer a more severe illness.

When we look at the research on cinnamon extract we see multiple studies showing cinnamon directly reduces both diabetes and obesity[105][105][107], reduces blood glucose, obesity, and blood pressure while offering protection against metabolic syndrome[108], improving body composition[108] inhibiting hyperlipidaemia and inflammation[110], and inducing increased fat loss[111].

Given the preponderance of evidence showing cinnamon can optimise body composition, help regulate glucose, and lower inflammation, it is perhaps no surprise that in common with berberine, oxymatrine and ecklonia cava, cinnamon looks yet another excellent micronutrient for supporting immunity. Indeed, the question worth exploring with all these ingredients is whether their antimicrobial properties are a direct result of inherent properties, or an indirect consequence of their effects on regulating blood sugar and improving body composition.

Whichever it is, their usage and the importance of maintaining optimal bodyfat levels cannot be stressed highly enough under the current circumstances.

For those interested in using berberine, oxymatrine, ecklonia cava tor cinnamon, there is one supplement which contains all four, Elixir by Hydrapharm.

Male Health & Testosterone - Crucial to Fighting Infection

Generally, as we age, levels of male hormones decline, this being one reason our ability to maintain optimal fitness and health is compromised as we age. A number of studies support the fact that testosterone or similar types of androgens such as androstenediol play a crucial role in combating influenza, augmenting immune system response, counteracting cortisol rises, and improving survival rates while helping to explain why elderly males suffer disproportionately from respiratory infections compared to younger men.[28][29]

Indeed, evidence shows that by increasing levels of testosterone you can both reduce the severity of respiratory infections and reduce mortality.[30][31] Furthermore, with increasing awareness of the role of inflammation as a key factor in driving disease severity and mortality, one study showed that lowered levels of testosterone, resulted in greater inflammation and mortality after influenza infection.[32]

One last thing to consider is that research showing that both young males (<age 20) and eldery men (>age 80) have a higher rate of hospitalisation and mortality which appears to suggest it is the level of circulating androgens like testosterone that is correlated with infection severity, potentially more than age, at least with some pathogens.[33]

The conclusion is that supporting optimal male testosterone function, is a pathway to improved immune support with a wide range of products available to support testosterone output for older men or those wanting a boost.

When it comes to products designed to support testosterone levels for men, the greatest benefit tends to come with those products designed to suppress estrogen levels in men. In simple terms, by reducing estrogen, your body produces more testosterone. In addition, for men who are overweight, such products could be even more vital as being overweight leads to higher estrogen levels in men and so such products are needed even more.

Of the available products we stock, the ingredients in the product Alchemy have shown the greatest evidence in both research and in real world feedback. You can read more about the studies supporting its efficacy on the Alchemy product page

ManTaking Testosterone Booster

Salidroside - Antiviral Properties & Proven in Athletes

Salidroside is the most biologically active constituent in the herb rhodiola rosea. It is typically used for its anti-stress/cognitive benefits with one study stating it works due to its ability to regulate stress response, inhibit oxidative stress, enhance neural regeneration and exert anti-inflammatory benefits[34]. Its ability to regulate stress and reduce inflammation is matched by its consistent antiviral activity with research showing it can combat dengue fever[35], coxsackievirus B3,[36] and respiratory viral infections.[37]

Most interestingly, is Salidroside’s potential antiviral properties for athletes. In a study from 2015, competitive athletes were given either a rhodiola supplement or placebo and the authors concluded that supplementing with “rhodiola may exert protective effects against virus replication following intense and prolonged exercise by inducing antiviral activity.” With this study using a lower purity of salidroside, there exists the potential for even more marked antiviral action for isolated salidroside.[38]

Finally, numerous studies have shown Salidroside’s potential in ameliorating sepsis induced lung injury[39], and protection against pulmonary fibrosis.[40][41] 

BPC-157 - Tremendous Evidence of Healing Properties

To list just a few BPC-157 benefits, a pentadecapeptide based amino acid a study from 2018 reveals that BPC-157 was able to counteract severe lesions induced by excessive intakes of alcohol, indeed, BPC-157 completely cured all alcohol lesions.[43]

BPC-157 has also been shown to have strong healing properties in both regenerating skin damage, and damage to the colon[44]. completely counteract the negative effects of NSAID overdoses to multiple body organs including the liver , protect the liver[45], brain, reduce arthritic pain, alleviate disturbances of body temperature, and improve blood vessel function to name but a few of the areas where BPC-157 was shown to be highly effective.[46][47][48]

BPC-157 was shown to reverse even severe lung damage in at least two studies.[49][50]

We have covered only a fraction of the research conducted into BPC-157 but we have yet to come across a single study where it failed to help improve symptoms associated with a particular condition. One area that has not been studied to date is whether it has any benefits in preventing or treating infectious diseases such as influenza but what we can say is that some of the damage associated with such diseases occurs in organs such as the lungs, and BPC-157 has been shown to promote recovery in such organs where the injury occurred through a different mechanism than an infectious disease.

Echinacea - Herb for Immune Support

Echinacea– Arguably the best known supplement for immunity, Echinacea is a herb which has a long history of use for reducing the incidence of sickness and for reducing the time people are sick for, as well as lowering symptom severity. These benefits are acknowledged even by leading hospitals and public healthcare systems.[51][52]

Echinacea is mooted to have anti-viral and anti-inflammatory properties with evidence showing its utility against influenza, swine flu and avian influenza.[53][54][55]

Vitamin C - Reduces Cold Duration, Severity and Incidence for Athletes

Vitamin C is arguably the supplement that springs to mind for the general public if asked for a nutrient that could help with immunity. Vitamin C plays a key role in the production of immune cells and is often used in hospital environments to help support patients’ immunity.

A meta-analysis of 29 studies investigated the use of over 200mg per day of vitamin C in preventing and treating the common cold. They noted that while the ingestion of vitamin C did not reduce the incidence of those falling ill, it did reduce the time to recovery in a way that was both modest and consistent. However, in situations where the study participants were exposed to extreme physical stress (high levels of exercise), vitamin C halved the risk of developing the common cold. In other words, for those engaging in regular, intensive bouts of exercise, vitamin C would be a particularly appropriate supplement to use on a daily basis as it not only reduces the duration of having a cold but also helps ensure you are less likely to catch them.

Furthermore, a separate study noted that vitamin C was able to enhance immune cell action and decrease lung inflammation caused by influenza viruses, as well as to reduce the duration and severity of the common cold.[56][57]

Vitamin D - Helps Prevent Respiratory Infections

Widely deficient in countries in temperate or cold climates, a 2011 study in the British Journal of Nutrition noted a linear association between Vitamin D status and seasonal infections stating “the prevalence of respiratory infections had a strong seasonal pattern in the opposite direction to the pattern of vitamin D concentrations”[58]

A meta-analysis for the British Medical Journal,[59] published in 2017, reviewed 25 high quality studies involving double-blind, placebo controlled trials involving vitamin D and concluded “Vitamin D supplementation reduced the risk of acute respiratory tract infection among all participants”.

This confirms Vitamin D’s place as among the most highly regarded supplements for supporting health and wellbeing.

Does that mean you should worry about taking too much vitamin D?

Looking into the results more closely, it turns out that the bolus doses being given participants were at least 30,000IU, this dose coming on top of their regular daily or weekly vitamin D doses. Given that general guidelines for vitamin D supplementation are anywhere between 1,000 and 4,000IU daily, a dose of 30,000IU in addition to a standardised daily dose looks extremely high and at least based on this review, had a negative effect.

Zinc - Widely Deficient Mineral for Supporting Immune Status

Zinc is an essential mineral widely noted to be deficient among most populations, with athletes in particular at risk of “significantly lower” zinc status.[60]

Given zinc’s role in testosterone production as well, with deficiencies linked to lower testosterone levels[61], many athletes will be taking a ZMA supplement which would correct the types of deficiencies seen above. If not, we would highly recommend they do for testosterone support and improved sleep quality, if nothing else.

What about the role of zinc in immunity though?

Studies show zinc is important for immune function and limiting inflammation[62][63] with deficiencies associated with increased production of pro-inflammatory cytokines Of note, the high proportion of deaths in young adults during the Spanish Flu pandemic in 1918 was attributed to pro-inflammatory cytokine storms.[64]

One last study on zinc specifically looked at how zinc deficiency contributed to an increased risk of infection with influenza, while those took supplemental zinc had a significantly lower risk of contracting pneumonia requiring antibiotics than those who did not supplement with zinc.[65]


Ashwagandha, is an adaptogenic herb which a multitude of experimental studies outlining its bioactive properties. One of the main features of Ashwagandha is its calming effects on the body which is associated with an overall stress-protective activity. A recent study found individuals supplemented with Ashwagandha improved their concentration and attention on all tests, but most notably their mood was improved[121].

A further study concluded it was beneficial in reducing stress and anxiety especially in those who had issues with sleeping. With both stress and lack of sleep being linked to poor immunity, you would expect Ashwagandha to help support immunity, but does it?[122]

As it happens, studies have shown just that with Ashwagandha being shown to have a "broad range of medicinal properties including anti-viral activity" including anti-influenza activity[123] as well as evidence indicating ashwagandha can enhance immunity, due to the link between stress and immune status. In other words, ashwagandha supplementation, by fighting stress, has the benefit of supporting immunity also[124].

Stress is a big issue for the entire world right now, with lockdowns being associated with increased metal distress in and of themselves, let alone when you add in the extra stress of coping with a potentially deadly virus or the economic pain it is causing. This makes Ashwagandha particularly relevant for anyone who is experiencing mental stress.

Vitamin E - Fat-Soluble Vitamin Most are Deficient in. [66]

While there is research indicating potential benefits of vitamin E supplementation in reducing the risk of contracting cancer,[67][68][69] and Parkinson’s disease[70], we investigated studies its effects on immune function.

A 2018 review looked at 14 studies in humans[71] and stated “many studies provided evidence that the immunostimulatory effects of vitamin E confer improved resistance to infections” but that the “magnitude of the effects were rather small” or “only observed in subgroups of subjects”. However, the effects of vitamin E supplementation specifically with respect to respiratory infections caused by influenza virus, shows that vitamin E supplementation helped to enhance influenza viral clearance[72] or helped defend against influenza infection.[73]

Finally, human studies using vitamin E showed a lower incidence of pneumonia among smokers[74], less incidence of respiratory infections[75], and a reduction in episodes of the common cold . [76]

Female Health and Estrogen

In general females tend to handle pathogenic respiratory viruses with the caveat that the poorer male response is likely linked to age-related declines in hormones such as testosterone.[77]

A number of nutrients have been shown to have both estrogenic and/or beneficial effects relating to respiratory disease, of which some of the better-known ones with promise include angelica sinensis, vitamin D, chasteberry extract, and soy isoflavones.[78][79][80][81]

Probiotics - Reduced Upper Respiratory Tract Infections in Athletes

Probiotics remain a confusing category due to the multiple strains of different probiotic ingredients, and variance in doses. Still, studies show probiotics outperformed a placebo in reducing the incidence of upper respiratory tract infections[82], significantly outperformed a placebo among an elderly population in a nursing home[83], improved survival rate in mice infected with two particularly virulent forms of influenza[84] and significantly reduced the incidence of upper respiratory infection and flu-like symptoms.[85]

Of particular note, there is evidence supporting the ability of probiotic supplements to reduce the incidence of upper respiratory tract infections in trained athletes when they consumed a multi-species probiotic supplement.[86]

When it comes to supplementing with a probiotic, one range of probiotics that has an excellent evidence base is the Neobium range.


Elderberries are a fruit from the Sambucus tree, the most common of which is Sambucus nigra. It has a long history of use in traditional medicine that goes back centuries but it is only more recently that it has grown in popularity as a potential treatment option for those suffering from colds or flu.

A review of the clinical research on elderberries in 2009[134], stated that it may "provide antioxidant, antiviral and antiproliferative effects in vitro" but that more research was needed in vivo although one trial in humans showed it "may be useful for the treatment of viral influenza infections".

An earlier study from 2004 which was placebo controlled and involved sixty patients, showed that those taking an elderberry preparation had symptomatic relief occurring four days earlier than the placebo group[135]. While admittedly a small trial, this is promising for those considering the use of an elderberry supplement during cold or flu season.

A more recent study from 2016 looked at whether elderberry supplementation could help with cold symptoms and duration, concluding that "placebo group participants had a significantly longer duration of cold episode days (117 vs 57) and the average symptom score over these days was also significantly higher." In short, the duration of the cold was shorter and the symptoms more mild in those who took elderberry.

Finally, a 2011 study uncovered both that elderberry supplementation could help protect against cold and flu but that it showed antibacterial as well as antiviral activity and in the authors' words "is active against human pathogenic bacteria as well as influenza viruses." One reason they looked into elderberry's anti-bacterial effects was that one of the risks with the influenza virus is bacterial super-infection causing severe pneumonia. In showing that elderberry had anti-bacterial effects, albeit in vitro, it demonstrates further the potential benefits in supplementing with this nutrient.

For those interested in using elderberry supplements, note that the doses in the studies mentioned range from 650mg to 1500mg in the various studies using elderberry capsules.


Selenium is a mineral which is required in only trace amounts by humans but which is nevertheless often deficient in humans. Best known as an antioxidant, selenium is has been gaining greater awareness for its potential to impact your response to infection.

In one study published in 2019, selenium deficiency was associated with heightened pathogenicity of several viruses[131], indicating adequate selenium intake is important for maintaining optimal immune status. However, while adequate intake of any essential micronutrient is important, a study from 2017 showing mixed effects, some beneficial and some detrimental, suggests selenium supplementation should be approached with caution[132].

Set against this, a 2015 study in Advanced in Nutrition[133], highlighted that with viral and bacterial infections associated with selenium deficiency, selenium supplementation improved several clinical and lifestyle variables in patients co-infected with HIV and tuberculosis. This included enhanced grip strength, increases in weight, decreases in mortality, slower disease progression, and suppressed viral loads. Certainly, with the studies using 100mcg to 400mcg a day, with the majority dosed at 200mcg it seems that if you already suffer from an infectious disease, it will generally pay off to supplement with some selenium due to its wide-ranging benefits.


Long touted by natural health practitioners as having antibacterial or antifungal properties, garlic has only been studied for its effects on human immunity relatively recently with research indicating it has the capacity to increase proliferation of natural killer cells and reduce cold and flu symptoms but not reducing the chance of catching either infection[136][137].

While the effects of garlic with flu and cold were limited to reducing symptom severity and enhancing natural killer cell production, there are other compelling reasons to consume garlic when we consider the evidence showing it can ameliorate inflammation[138], lower blood pressure, and stimulate immune function more broadly[139].


Yet another of the antioxidants on this list alongside selenium, vitamin C and vitamin E, N-acetylcysteine (NAC) has been a popular supplement for those concerned with counteracting free radical damage caused by oxidative processes in the body. As with the aforementioned antioxidants, it is commonly found in numerous antioxidant supplements so how well does it stack up for the specific purpose of upholding immunity and/or combating infectious disease symptoms?

Fortunately, NAC is one of the more studied ingredients in this list with various studies showing that high doses of NAC could help counteract pneumonia and septic shock triggered by the swine flu pandemic of 2009[125], that it helped combat acute lung injury caused by the same infectious disease[126], NAC led to a "dramatic decrease in influenza virus production" in a 2018 study[127] while a 2010 study indicated NAC had the ability to inhibit virus replication and combat pro-inflammatory effects associated with the particularly deadly H5N1 form of influenza better known as Bird Flu[128].

Furthermore, NAC was also shown to help attenuate the effects of influenza and reduce the incidence of clinically apparent disease although it did not reduce the incidence of contracting influenza[129]. Set against the prior research, a different study showed that NAC, while capable of inhibiting the H1N1 influenza virus (swine flu) in vitro, was not effective against it in vivo and thus cannot be considered to be universally effective against all types of influenza viruses. It is worth noting that the specific strain this study looked at is not a seasonal flu virus but instead one that circulated widely in 2009[130].

In conclusion, while there is a broad research basis documenting multiple health benefits that favour steady state supplementation of NAC, the evidence supporting its use agains influenza type viruses is not as strong as it is in providing protection from the effects of other illnesses.

Green Tea - Antioxidant for General Health

One study investigated whether green tea could show anti-influenza action in chickens infected with the H1N1 strain and results revealed that in a dose-dependent manner, green tea consumption was indeed associated with strong anti-influenza activity.[101]

A different study investigated whether tea catechins found in green tea could be beneficial in cases of infection with both influenza and the common cold.[102] The authors concluded that while the antiviral activity of catechins had been demonstrated, and epidemiological studies have suggested regular green tea consumption decreases influenza infection rates and cold symptoms, there is nevertheless the need for more clinical evidence to support their utility.

We do not know at this stage if green tea consumption in humans is specifically beneficial in preventing or ameliorating symptoms of infectious diseases but in both animals and in vitro studies, consumption of green tea can help inhibit viral replication.


Spirulina is a plant based superfood which is rich in protein and loaded with micronutrients including vitamins, minerals and essential fatty acids. For this alone, supplementing with spirulina is a great idea for ensuring you meet both your macro and micronutrient requirements.

As far as the research on its health benefits, we see that there is research showing spirulina consumption can prevent skeletal muscle damage and stimulate antibody production and anti-inflammatory responses when subjected to exercise-induced stress[140], inhibit influenza virus replication and reduced virus-induced mortality in mice when multi-gram doses were used[141] and reduced clinical signs of disease caused by the H1N1 strain of influenza. Again though, this was in a study conducted in mice.[142]

While there is some limited evidence indicating potential antioxidant and immunomodulating benefits in supplementing spirulina, they occur mainly in animal or in vitro studies[143], with more human evidence required. What little human research that has been documented, for example a review on whether spirulina can help with metabolic syndrome showed only limited evidence supporting its consumption.[144]

All in all, spirulina looks like a great choice of food but at this stage the evidence supporting its use is more theoretical than clinically validated. For those who wish to read more about its potential applications, a recently published paper gives various reasons for supplementing with spirulina, along with various other nutrients, some of which we have covered, but including others like glycine and glucosamine which we have not. Our view is that without clinical validation, such theoretical arguments often fail to demonstrate real-world benefits although the suggested doses of the different ingredients presented by the authors could have benefits in other ways.[145]

Green Tea Health Supplement

Practices to Support Immunity and Prevent Infections

A quick word on non-nutrient based interventions that support immunity and help reduce your chances of contracting an infectious disease in the first place.

We would strongly advise anyone seeking to focus on prevention and immune system support to focus on these first. They have the strongest evidence base of all approaches to ensuring you stay healthy and any use of supplements should be done after you have incorporated these into your daily life.

coronavirus health tips


Personal Hygiene Aim to wash your hands for 30 secs with warm water and soap. Wash your hands every hour or less. After washing your hands, we recommend disposable paper towels, to dry your hands.


Keep our surgical scrub sanitising spray by your side when you are out. Designed for operating theatre staff, it is far superior than a regular supermarket hand sanitiser
A Healthy, Nutritious Diet Aim to eat 5 portions of fruit or veg daily + above maintenance calories, 6-10g of omega 3’s and at least 1g/kg of protein per bodyweight.
Control Inflammation Inflammation is a risk factor in numerous diseases, including the flu [8], so aim to consume a diet that limits inflammation.


Protein - In general, eat more lean sources of protein like low fat cuts of meat, fish of all kinds, and whey protein. Most protein rich food has a minimal impact on inflammation with the exception of higher fat cuts of red meat or processed meats like burgers, bacon and sausages.


Carbohydrates - Aim to consume mainly non-processed sources such as rice, pasta, oats, but avoiding wheat if you struggle with gluten. Eating lots of cruciferous vegetables like broccoli, and cauliflower is great but avoid again heavily processed foods like French fries, sodas, and refined bread.


Fats – Most fat intake will tend to be incidental to the consumption of other foods which if carefully selected as above, should mean the only real fats you should look to include are foods rich in beneficial fats such as omega-3 fatty acids found in sardines and mackerel and other oily fish.


Alternatively, if those aren’t to your fancy, you can supplement your diet with fish oil as found in Predator Super Omega - a high quality EPA/DHA rich fish oil supplement.
Avoid Smoking/Vaping Smoking massively increases the incidence and severity of respiratory infections with studies estimating it makes you up to 14 times as likely to die or get severe illness than non-smokers [9] with both smoking and e-cigarettes leading to worse outcomes with respiratory infections.[10]
Minimise exposure to sick people Stay away from those who are sick and try to avoid going within 6 feet of those who appear well as they could be asymptomatic and still highly infectious. Respiratory droplets are a key transmission mechanism but so would any skin to skin contact.
Hydration Aim to drink around 3 litres of water daily for general health.
Sleep Aim for 8 hrs of sleep a night if possible. Avoid blue light emitting sources and your phone in the hour before bed. Try a research backed supplement like Revival which incorporates ingredients has been shown to help attenuate stress, anxiety and aid in deeper, more restorative sleep. Explore our full range of sleep supplements.
Stress Meditation, drinking chamomile tea, watching Netflix, avoid too much bad news– do what you must to help you relax especially at night. The same supplements designed for sleep can in most cases be repurposed for stress support – good options include Revival, Ashwagandha and CBD products.


Bonus: Ashwagandha also helps with hormonal regulation which we touch on below plays a key role in severity of outcomes for some respiratory viral infections.
Disinfect Surfaces A study in Singapore on Coronavirus infected patients[11] found that surfaces needed to be regularly cleaned with an antimicrobial disinfectant. If this was done, the rooms were clear of coronavirus despite hosting infected patients.


Another room containing a patient was examined before cleaning. In this situation the virus had contaminated 13 out of 15 room sites including air outlet fans, and the toilet bowl, sink and door handles.


The lesson is to clean surfaces regularly, including phones, door handles, laptops, desks, fridge doors – ANYTHING you touch should be cleaned regularly.


The good news in this study, is that despite the surfaces being contaminated, the virus was not present in the air, those tests being negative despite widespread contamination elsewhere.
Avoid touching your eyes, nose and mouth Scratch your head if you must, touch your forehead by all means but never touch an area with your fingers which acts as a pathogen entry point. If you absolutely must because of an itch, wrap your fingers in tissue paper or else do so immediately after washing your hands. If you can use your feet, elbows or shoulders to open doors.
Exercise Aim to exercise 3-4 times a week. Avoid daily high intensity exercise as this can make you more likely to fall ill and be wary of ramping up exercise intensity or volume too quickly. For those who are training heavily in particular, we highly recommend supplementing those supplements shown to be effective in hard training athletes for protecting against infections.
Stay Fit and Lean While this might seem linked to the importance of exercise, excessive bodyfat is a risk factor in and of itself[12]. To be sure, the link is strongest in those classified as obese, but there exists a sliding scale between the health of someone having an optimum level of body fat and those who are extremely overweight[13].


As such, we should all strive to maintain our body composition at a level that is optimal, avoiding also the temptation to diet down to extremely low levels of bodyfat seen among competition bodybuilders or some endurance cyclists as that can make you more susceptible to illness.

Final Words

Of course, there is no guarantee that any action an individual takes, can prevent them falling sick but by prioritising their lifestyle habits and then supplementing with carefully selected nutrients based on scientific evidence, we can ensure that we do what we can to optimise our wellbeing as far as we can.

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[6] Long-term bone and lung consequences associated with hospital-acquired severe acute respiratory syndrome: a 15-year follow-up from a prospective cohort study (2020): Peixun Zhang, Jia Li, Huixin Liu, Na Han, Jiabao Ju, Yuhui Kou, Lei Chen, Mengxi Jiang, Feng Pan, Yali Zheng, Zhancheng Gao & Baoguo Jiang

[7] Altered Lipid Metabolism in Recovered SARS Patients Twelve Years after Infection (2017): Qi Wu, Lina Zhou, Xin Sun, Zhongfang Yan, Chunxiu Hu, Junping Wu, Long Xu, Xue Li, Huiling Liu, Peiyuan Yin, Kuan Li, Jieyu Zhao, Yanli Li, Xiaolin Wang, Yu Li, Qiuyang Zhang, Guowang Xu & Huaiyong Chen

[8] Inflammation induced by influenza virus impairs human innate immune control of pneumococcus (2018): Jochems SP1, Marcon F2, Carniel BF3, Holloway M3, Mitsi E3, Smith E3, Gritzfeld JF3, Solórzano C3, Reiné J3, Pojar S3, Nikolaou E3, German EL3, Hyder-Wright A3,4, Hill H3,4, Hales C3,4, de Steenhuijsen Piters WAA5,6,7, Bogaert D5,6,7, Adler H3, Zaidi S3, Connor V3,4, Gordon SB3,8, Rylance J3, Nakaya HI9, Ferreira DM10.

[9] Analysis of factors associated with disease outcomes in hospitalized patients with 2019 novel coronavirus disease (2020): Liu, Wei1; Tao, Zhao-Wu2; Lei, Wang1; Ming-Li, Yuan1; Kui, Liu3; Ling, Zhou3; Shuang, Wei3; Yan, Deng3; Jing, Liu4; Liu, Hui-Guo3; Ming, Yang5; Yi, Hu1 Section Editor(s): Wei, Pei-Fang




[13] Diseases and Disorders Associated with Excess Body Weight (2011): Joseph A. Knight

[14] Anti-influenza activity of berberine improves prognosis by reducing viral replication in mice (2018): Yan YQ, Fu YJ, Wu S, Qin HQ, Zhen X, Song BM, Weng YS, Wang PC, Chen XY, Jiang ZY

[15] Discovery of berberine based derivatives as anti-influenza agent through blocking of neuraminidase (2017)" Enkhtaivan G, Muthuraman P, Kim DH, Mistry B.

[16] In vivo and in vitro antiviral effects of berberine on influenza virus (2011): Wu Y, Li JQ, Kim YJ, Wu J, Wang Q, Hao Y.

[17] Oxymatrine Inhibits Influenza A Virus Replication and Inflammation via TLR4, p38 MAPK and NF-κB Pathways (2018): Dai JP, Wang QW, Su Y, Gu LM, Deng HX, Chen XX, Li WZ, Li KS.

[18] Antimicrobial, Antioxidant, and Anticancer Activities of Biosynthesized Silver Nanoparticles Using Marine Algae Ecklonia cava (2016): Jayachandran Venkatesan,1 Se-Kwon Kim,2 and Min Suk Shim1,*

[19] Evaluation of antioxidant properties of a new compound, pyrogallol-phloroglucinol-6,6'-bieckol isolated from brown algae, Ecklonia cava (2011): Sung-Myung Kang,1,* Seung-Hong Lee,1,* Soo-Jin Heo,2 Kil-Nam Kim,3 and You-Jin Jeoncorresponding author1

[20] Metabolites of Seaweeds as Potential Agents for the Prevention and Therapy of Influenza Infection (2019): Natalia Besednova,1 Tatiana Zaporozhets,1 Tatiana Kuznetsova,1 Ilona Makarenkova,1 Lydmila Fedyanina,2 Sergey Kryzhanovsky,2 Olesya Malyarenko,3 and Svetlana Ermakova3,

[21] Influenza virus neuraminidase inhibitory activity of phlorotannins from the edible brown alga Ecklonia cava (2011): Ryu YB1, Jeong HJ, Yoon SY, Park JY, Kim YM, Park SJ, Rho MC, Kim SJ, Lee WS.

[22] Characterizing Eckol as a Therapeutic Aid: A Systematic Review (2019): Bandana Manandhar,1 Pradeep Paudel,1 Su Hui Seong,1 Hyun Ah Jung,2,* and Jae Sue Choi1,

[23] In vitro antiviral activity of phlorotannins isolated from Ecklonia cava against porcine epidemic diarrhea coronavirus infection and hemagglutination (2013): Kwon HJ1, Ryu YB, Kim YM, Song N, Kim CY, Rho MC, Jeong JH, Cho KO, Lee WS, Park SJ.

[24] Virucidal and Synergistic Activity of Polyphenol-Rich Extracts of Seaweeds against Measles Virus (2018): Karla Morán-Santibañez,1,2,* Mario A. Peña-Hernández,1 Lucia Elizabeth Cruz-Suárez,3 Denis Ricque-Marie,3 Rachid Skouta,4 Abimael H. Vasquez,2 Cristina Rodríguez-Padilla,1 and Laura M. Trejo-Avila1,

[25] Inhibition of HIV-1 reverse transcriptase and protease by phlorotannins from the brown alga Ecklonia cava (2004): Ahn MJ1, Yoon KD, Min SY, Lee JS, Kim JH, Kim TG, Kim SH, Kim NG, Huh H, Kim J.

[26] Anti-obesity effects of pectinase and cellulase enzyme-treated Ecklonia cava extract in high-fat diet-fed C57BL/6N mice (2018): In-Hye Kim,1 Jung-Wook Choi,2 Min-Kyeong Lee,2 Chang-Ju Kwon,3 and Taek-Jeong Nam1,2

[27] Enzyme-treated Ecklonia cava extract inhibits adipogenesis through the downregulation of C/EBPα in 3T3-L1 adipocytes (2017): In-Hye Kim1 and Taek-Jeong Nam1,2

[28] Endocrine regulation of the immune response to influenza virus infection with a metabolite of DHEA-androstenediol (1997): Padgett DA1, Loria RM, Sheridan JF.

[29] Androstenediol prevents neuroendocrine-mediated suppression of the immune response to an influenza viral infection (1999): Padgett DA1, Sheridan JF.

[30] Age and testosterone mediate influenza pathogenesis in male mice (2016): Landon G. vom Steeg,1 Meghan S. Vermillion,1,3 Olivia J. Hall,1 Ornob Alam,1 Ross McFarland,1 Haolin Chen,2 Barry Zirkin,2 and Sabra L. Klein

[31] Testosterone treatment of aged male mice improves some but not all aspects of age-associated increases in influenza severity (2020): Landon G. vom Steeg, Sarah E. Attreed, Barry Zirkin, Sabra L. Klein

[32] Age and testosterone effects on responses to influenza infection and vaccination. Klein, Sabra L.   

[33] Sex- and age-related differences in morbidity rates of 2009 pandemic influenza A H1N1 virus of swine origin in Japan (2011): Eshima N, Tokumaru O, Hara S, Bacal K, Korematsu S, Tabata M, et al.

[34] Pharmacological activities, mechanisms of action, and safety of salidroside in the central nervous system (2018): Zhifeng Zhong,1 Jing Han,1 Jizhou Zhang,1 Qing Xiao,1 Juan Hu,1,2 and Lidian Chen1,2

[35] Salidroside exhibits anti-dengue virus activity by upregulating host innate immune factors (2016): Sharma N1, Mishra KP2, Ganju L1.

[36] The in vitro and in vivo antiviral effects of salidroside from Rhodiola rosea L. against coxsackievirus B3 (2009): Wang H1, Ding Y, Zhou J, Sun X, Wang S.

[37] Antiviral activity of Salidroside from the leaves of Nigerian mistletoe (Loranthus micranthus Linn) parasitic on Hevea brasiliensis against respiratory syncytial virus (2017): Agbo MO, Odimegwu DC, Okoye FBC, Osadebe PO.

[38] Rhodiola rosea Exerts Antiviral Activity in Athletes Following a Competitive Marathon Race (2015): Ahmed M1, Henson DA1, Sanderson MC1, Nieman DC2, Zubeldia JM3, Shanely RA4.

[39] Salidroside ameliorates sepsis-induced acute lung injury and mortality via downregulating NF-κB and HMGB1 pathways through the upregulation of SIRT1 (2017): Lan KC1, Chao SC2, Wu HY3, Chiang CL3, Wang CC4, Liu SH4,5, Weng TI6,7.

[40] Salidroside protects against bleomycin-induced pulmonary fibrosis: activation of Nrf2-antioxidant signaling, and inhibition of NF-κB and TGF-β1/Smad-2/-3 pathways (2016): Tang H1, Gao L1, Mao J2, He H1, Liu J1, Cai X3, Lin H4, Wu T5

[41] [Salidroside improves pulmonary fibrosis by down-regulation of cathepsin B and NF-κBp65 in rats] (2017): Liu X1, Bai Y2, Liang L2, Feng J3, Deng F4.


[43] An endogeous defensive concept, renewed cytoprotection/adaptive cytoprotection: intra(per)-oral/intraastric strong alcohol in rat. Involvement of pentadecapeptide BPC 157 and nitric oxide system (2018): Becejac T1, Cesarec V1, Drmic D1, Hirsl D1, Madzarac G1, Djakovic Z1, Bunjevac I1, A Zenko Sever A2, Sepac A2, Batelja Vuletic L2, Stancic Rokotov D1, Seiwerth S2, Sikiric P3.

[44] BPC 157's effect on healing (1997): Seiwerth S, Sikiric P, Grabarevic Z, Zoricic I, Hanzevacki M, Ljubanovic D, Coric V, Konjevoda P, Petek M, Rucman R, Turkovic B, Perovic D, Mikus D, Jandrijevic S, Medvidovic M, Tadic T, Romac B, Kos J, Peric J, Kolega Z.

[45] Stable gastric pentadecapeptide BPC 157 can improve the healing course of spinal cord injury and lead to functional recovery in rats (2019): Darko Perovic, Danijela Kolenc, Vide Bilic, Nenad Somun, Domagoj Drmic, Esmat Elabjer, Gojko Buljat, Sven Seiwerth & Predrag Sikiric

[46] Toxicity by NSAIDs. Counteraction by stable gastric pentadecapeptide BPC 157 (2013): Sikiric P1, Seiwerth S, Rucman R, Turkovic B, Rokotov DS, Brcic L, Sever M, Klicek R, Radic B, Drmic D, Ilic S, Kolenc D, Aralica G, Safic H, Suran J, Rak D, Dzidic S, Vrcic H, Sebecic B.

[47] High hepatotoxic dose of paracetamol produces generalized convulsions and brain damage in rats. A counteraction with the stable gastric pentadecapeptide BPC 157 (PL 14736) (2010): Ilic S1, Drmic D, Zarkovic K, Kolenc D, Coric M, Brcic L, Klicek R, Radic B, Sever M, Djuzel V, Ivica M, Boban Blagaic A, Zoricic Z, Anic T, Zoricic I, Djidic S, Romic Z, Seiwerth S, Sikiric P.

[48] Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract (2011): Sikiric P, Seiwerth S, Rucman R, Turkovic B, Rokotov DS, Brcic L, Sever M, Klicek R, Radic B, Drmic D, Ilic S, Kolenc D, Vrcic H, Sebecic B.

[49] Lung lesions and anti-ulcer agents beneficial effect: anti-ulcer agents pentadecapeptide BPC 157, ranitidine, omeprazole and atropine ameliorate lung lesion in rats (2001): Stancic-Rokotov D1, Slobodnjak Z, Aralica J, Aralica G, Perovic D, Staresinic M, Gjurasin M, Anic T, Zoricic I, Buljat G, Prkacin I, Sikiric P, Seiwerth S, Rucman R, Petek M, Turkovic B, Kokic N, Jagic V, Boban-Blagaic A.

[50] Ethanol gastric lesion aggravated by lung injury in rat. Therapy effect of antiulcer agents (2001): Stancic-Rokotov D1, Sikiric P, Seiwerth S, Slobodnjak Z, Aralica J, Aralica G, Perovic D, Anic T, Zoricic I, Buljat G, Prkacin I, Gjurasin M, Rucman R, Petek M, Turkovic B, Ivasovic Z, Jagic V, Staresinic M, Boban-Blagaic A.



[53] Anti-viral properties and mode of action of standardized Echinacea purpurea extract against highly pathogenic avian influenza virus (H5N1, H7N7) and swine-origin H1N1 (S-OIV) (2009): Pleschka S, Stein M, Schoop R, Hudson JB.

[54] Induction of multiple pro-inflammatory cytokines by respiratory viruses and reversal by standardized Echinacea, a potent antiviral herbal extract(2009): Sharma M1, Anderson SA, Schoop R, Hudson JB.

[55] Echinacea in infection (2008): Diane F Birt, Mark P Widrlechner, Carlie A LaLone, Lankun Wu, Jaehoon Bae, Avery KS Solco, George A Kraus, Patricia A Murphy, Eve S Wurtele, Qiang Leng, Steven C Hebert, Wendy J Maury, and Jason P Price

[56] Treatment of the common cold (2007): Simasek M1, Blandino DA.

[57] Red ginseng and vitamin C increase immune cell activity and decrease lung inflammation induced by influenza A virus/H1N1 infection (2016): Kim H1,2, Jang M1, Kim Y1, Choi J1, Jeon J1, Kim J3, Hwang YI1, Kang JS1,2, Lee WJ1.

[58] Vitamin D status has a linear association with seasonal infections and lung function in British adults (2011): Berry DJ, Hesketh K, Power C, Hyppönen E.

[59] Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data (2017): Martineau et al.

[60] Lower Serum Zinc Concentration Despite Higher Dietary Zinc Intake in Athletes: A Systematic Review and Meta-analysis (2018): Chu A, Holdaway C, Varma T, Petocz P, Samman S.

[61] Zinc status and serum testosterone levels of healthy adults (1996): Prasad AS, Mantzoros CS, Beck FW, Hess JW, Brewer GJ

[62] Zinc and immunity: An essential interrelation (2016): Maria Maares, Hajo Haase

[63] Zinc and its role in immunity and inflammation (2015): Bonaventura P, Benedetti G, Albarède F, Miossec P.

[64] The cytokine storm of severe influenza and development of immunomodulatory therapy (2016): Qiang Liu, Yuan-hong Zhou, and Zhan-qiu Yang

[65] ZINC INTAKE AND RESISTANCE TO H1N1 INFLUENZA (2010): Harold H. Sandstead, MDcorresponding author and Ananda S. Prasad, MD, PhD

[66] A Systematic Review of Global Alpha-Tocopherol Status as Assessed by Nutritional Intake Levels and Blood Serum Concentrations (2015): Szabolcs Péter, Angelika Friedel, Franz F. Roos, Adrian Wyss, Manfred Eggersdorfer, Kristina Hoffmann and Peter Weber

[67] Association of Vitamin E Intake with Reduced Risk of Kidney Cancer: A Meta-Analysis of Observational Studies (2015): Chongxing Shen, Ying Huang, Shanhong Yi, Zhenqiang Fang,and Longkun Li

[68] Vitamin C and E intake and risk of bladder cancer: a meta-analysis of observational studies (2014): Yu-Yong Wang, Xu-Liang Wang and Zhi-Jian Yu

[69] Association of dietary vitamin E intake with risk of lung cancer: a dose-response meta-analysis (2017): Yong-Jian Zhu, Ya-Cong Bo, Xin-Xin Liu, Chun-Guang Qiu

[70] Intake of vitamin E, vitamin C, and carotenoids and the risk of Parkinson's disease: a meta-analysis (2005): Etminan M, Gill SS, Samii A

[71] The Role of Vitamin E in Immunity (2018): Ga Young Lee and Sung Nim Han

[72] Vitamin E supplementation decreases lung virus titers in mice infected with influenza (1997): Hayek MG, Taylor SF, Bender BS, Han SN, Meydani M, Smith DE, Eghtesada S, Meydani SN.

[73] Vitamin E supplementation increases T helper 1 cytokine production in old mice infected with influenza virus (2000): Han SN, Wu D, Ha WK, Beharka A, Smith DE, Bender BS, Meydani SN.

[74] Vitamin E administration may decrease the incidence of pneumonia in elderly males (2016): Hemila H.

[75] Vitamin E and respiratory tract infections in elderly nursing home residents: A randomized controlled trial (2004): Meydani S.N., Leka L.S., Fine B.C., Dallal G.E., Keusch G.T., Singh M.F., Hamer D.H.

[76] Vitamin C, vitamin E, and beta-carotene in relation to common cold incidence in male smokers (2002): Hemilä H., Kaprio J., Albanes D., Heinonen O.P., Virtamo J.

[77] The confluence of sex hormones and aging on immunity (2018): Gubbels Bupp MR, Potluri T, Fink AL, Klein SL

[78] Protective cardiovascular and renal actions of vitamin D and estrogen (2013): Pandu Gangula,1,4 Yuan–Lin Dong,3 Ayman Al-Hendy,2,4 Gloria Richard-Davis,2,4 Montgomery-Rice Valerie,2,4 Georges Haddad,5 Richard Millis,5 Susanne B. Nicholas,6 and Diane Moseberry7

[79] Natural medicine: the genus Angelica (2004): Sarker SD1, Nahar L.

[80] Using Complementary and Alternative Medicines to Target the Host Response during Severe Influenza (2009): Alleva LM1, Cai C, Clark IA.

[81] Botanicals and Their Bioactive Phytochemicals for Women's Health (2016): Dietz BM1, Hajirahimkhan A1, Dunlap TL1, Bolton JL2.

[82] Prevention and Treatment of Influenza, Influenza-Like Illness, and Common Cold by Herbal, Complementary, and Natural Therapies (2017): Mousa HA

[83] Probiotics to Prevent Respiratory Infections in Nursing Homes: A Pilot Randomized Controlled Trial (2018): Wang B1, Hylwka T1, Smieja M1, Surrette M2, Bowdish DME1, Loeb M1.

[84] Effects of Lactobacillus plantarum and Leuconostoc mesenteroides Probiotics on Human Seasonal and Avian Influenza Viruses (2018): Bae JY1, Kim JI1, Park S1, Yoo K1, Kim IH2, Joo W3, Ryu BH3, Park MS1, Lee I1, Park MS1.

[85] Prospective study of probiotic supplementation results in immune stimulation and improvement of upper respiratory infection rate (2018): Zhang H1, Yeh C2, Jin Z3, Ding L2, Liu BY4, Zhang L5, Dannelly HK4.

[86] Probiotic Supplements Beneficially Affect Tryptophan-Kynurenine Metabolism and Reduce the Incidence of Upper Respiratory Tract Infections in Trained Athletes: A Randomized, Double-Blinded, Placebo-Controlled Trial (2016): Strasser B, Geiger D, Schauer M, Gostner JM, Gatterer H, Burtscher M, Fuchs D.

[87] Selenium, Selenoproteins and Viral Infection (2019): Guillin OM, Vindry C, Ohlmann T, Chavatte L.

[88] Dietary Selenium in Adjuvant Therapy of Viral and Bacterial Infections (2015): Holger Steinbrenner, Saleh Al-Quraishy, Mohamed A Dkhil, Frank Wunderlich, and Helmut Sies

[89] Aged Garlic Extract Modifies Human Immunity (2016): Percival SS

[90] Supplementation with aged garlic extract improves both NK and γδ-T cell function and reduces the severity of cold and flu symptoms: a randomized, double-blind, placebo-controlled nutrition intervention (2012): Nantz MP, Rowe CA, Muller CE, Creasy RA, Stanilka JM, Percival SS.

[91] Aged garlic extract supplementation modifies inflammation and immunity of adults with obesity: A randomized, double-blind, placebo-controlled clinical trial (2018): Xu C1, Mathews AE1, Rodrigues C1, Eudy BJ1, Rowe CA1, O'Donoughue A1, Percival SS2.

[92] Garlic Lowers Blood Pressure in Hypertensive Individuals, Regulates Serum Cholesterol, and Stimulates Immunity: An Updated Meta-analysis and Review (2016): Ried K

[93] High-Dose N-Acetylcysteine Therapy for Novel H1N1 Influenza Pneumonia (2010): Kang Yiu Lai, MRCP; Wing Yiu Ng, MRCP; Pik Kei Osburga Chan, MRCP; Kit Fai Wong, MD, MRCP; Fanny Cheng, MRCP

[94] N-acetyl-l-cystine (NAC) protects against H9N2 swine influenza virus-induced acute lung injury (2014): hang RH1, Li CH1, Wang CL1, Xu MJ1, Xu T2, Wei D1, Liu BJ1, Wang GH1, Tian SF1.

[95] Bax Inhibitor-1 Acts as an Anti-Influenza Factor by Inhibiting ROS Mediated Cell Death and Augmenting Heme-Oxygenase 1 Expression in Influenza Virus Infected Cells (2018): Hossain MK1, Saha SK2, Abdal Dayem A3, Kim JH4, Kim K5, Yang GM6, Choi HY7, Cho SG8.

[96] N-acetyl-L-cysteine (NAC) inhibits virus replication and expression of pro-inflammatory molecules in A549 cells infected with highly pathogenic H5N1 influenza A virus (2010): Geiler J1, Michaelis M, Naczk P, Leutz A, Langer K, Doerr HW, Cinatl J Jr.

[97] Attenuation of influenza-like symptomatology and improvement of cell-mediated immunity with long-term N-acetylcysteine treatment (1997(: De Flora S1, Grassi C, Carati L.

[98] The antioxidant, immunomodulatory, and anti-inflammatory activities of Spirulina: an overview (2016): Wu Q, Liu L, Miron A, Klímová B, Wan D, Kuča K.

[99] Well-tolerated Spirulina extract inhibits influenza virus replication and reduces virus-induced mortality (2016): Chen YH, Chang GK, Kuo SM, Huang SY, Hu IC, Lo YL, Shih SR

[100] Oral administration of a Spirulina extract enriched for Braun-type lipoproteins protects mice against influenza A (H1N1) virus infection (2015): Pugh ND, Edwall D, Lindmark L, Kousoulas KG, Iyer AV, Haron MH, Pasco DS.

[101] Anti-influenza virus activity of green tea by-products in vitro and efficacy against influenza virus infection in chickens (2012): Lee HJ, Lee YN, Youn HN, Lee DH, Kwak JH, Seong BL, Lee JB, Park SY, Choi IS, Song CS.

[102] Effect of Tea Catechins on Influenza Infection and the Common Cold with a Focus on Epidemiological/Clinical Studies (2018): Furushima D, Ide K, Yamada H.

[103]Cheng B.C. A review of cinnamon. Zhong Cao Yao. 1983;14:134.

[104]Fabio A, Cermelli C, Fabio G, Nicoletti P, Quaglio P. Screening of the antibacterial effects of a variety of essential oils on microorganisms responsible for respiratory infections. Phytother Res. 2007;21:374–377. doi: 10.1002/ptr.1968

[105]Reduced obesity, diabetes, and steatosis upon cinnamon and grape pomace are associated with changes in gut microbiota and markers of gut barrier (2018): Van Hul M et al.

[106]How effective are antioxidant supplements in obesity and diabetes? (2015): Abdali D1, Samson SE, Grover AK.

[107]Molecular mechanisms of the anti-obesity effect of bioactive ingredients in common spices: a review (2018): Lu M 1, Cao Y , Xiao J , Song M , Ho CT.

[108] Effect of oral cinnamon intervention on metabolic profile and body composition of Asian Indians with metabolic syndrome: a randomized double -blind control trial (2017): Gupta Jain S1, Puri S1, Misra A2, Gulati S3,4, Mani K5.

[109] Cinnamon effects on metabolic syndrome: a review based on its mechanisms (2016): Mollazadeh H1, Hosseinzadeh H2.

[110] Cinnamon Polyphenol Extract Inhibits Hyperlipidemia and Inflammation by Modulation of Transcription Factors in High-Fat Diet-Fed Rats (2017): Tuzcu Z1, Orhan C2, Sahin N2, Juturu V3, Sahin K2.

[111] Cinnamon induces browning in subcutaneous adipocytes (2017): Kwan HY et al.

[121]Effects of an Adaptogenic Extract on Electrical Activity of the Brain in Elderly Subjects with Mild Cognitive Impairment: A Randomized, Double-Blind, Placebo-Controlled, Two-Armed Cross-Over Study (2020): Dimpfel W1, Schombert L2, Keplinger-Dimpfel IK2, Panossian A3.

[122] Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study (2019): Salve J1, Pate S2, Debnath K3, Langade D4.

[123] Cai, Z., Zhang, G., Tang, B., Liu, Y. 2015. Promising Anti-influenza Properties of Active Constituent of Withania somnifera Ayurvedic Herb in Targeting Neuraminidase of H1N1 Influenza: Computational Study. 72(3): 727-39

[124] Immune enhancing effects of WB365, a novel combination of Ashwagandha (Withania somnifera) and Maitake (Grifola frondosa) extracts (2011): Vaclav Vetvicka and Jana Vetvickova

[125] High-Dose N-Acetylcysteine Therapy for Novel H1N1 Influenza Pneumonia (2010): Kang Yiu Lai, MRCP; Wing Yiu Ng, MRCP; Pik Kei Osburga Chan, MRCP; Kit Fai Wong, MD, MRCP; Fanny Cheng, MRCP

[126] N-acetyl-l-cystine (NAC) protects against H9N2 swine influenza virus-induced acute lung injury (2014): hang RH1, Li CH1, Wang CL1, Xu MJ1, Xu T2, Wei D1, Liu BJ1, Wang GH1, Tian SF1.

[127] Bax Inhibitor-1 Acts as an Anti-Influenza Factor by Inhibiting ROS Mediated Cell Death and Augmenting Heme-Oxygenase 1 Expression in Influenza Virus Infected Cells (2018): Hossain MK1, Saha SK2, Abdal Dayem A3, Kim JH4, Kim K5, Yang GM6, Choi HY7, Cho SG8.

[128] N-acetyl-L-cysteine (NAC) inhibits virus replication and expression of pro-inflammatory molecules in A549 cells infected with highly pathogenic H5N1 influenza A virus (2010): Geiler J1, Michaelis M, Naczk P, Leutz A, Langer K, Doerr HW, Cinatl J Jr.

[129] Attenuation of influenza-like symptomatology and improvement of cell-mediated immunity with long-term N-acetylcysteine treatment (1997(: De Flora S1, Grassi C, Carati L.

[130] N-acetylcysteine lacks universal inhibitory activity against influenza A viruses (2011): Garigliany MM, Desmecht DJ.

[131]Selenium, Selenoproteins and Viral Infection (2019): Guillin OM, Vindry C, Ohlmann T, Chavatte L.

[132] Selenium supplementation has beneficial and detrimental effects on immunity to influenza vaccine in older adults (2017): Ivory K1, Prieto E2, Spinks C3, Armah CN4, Goldson AJ5, Dainty JR6, Nicoletti C7.

[133] Dietary Selenium in Adjuvant Therapy of Viral and Bacterial Infections (2015): Holger Steinbrenner, Saleh Al-Quraishy, Mohamed A Dkhil, Frank Wunderlich, and Helmut Sies

[134] A systematic review on the sambuci fructus effect and efficacy profiles (2009): J. E. Vlachojannis M. Cameron S. Chrubasik

[135] Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections (2004): Zakay-Rones Z, et al. J

[136]Aged Garlic Extract Modifies Human Immunity (2016): Percival SS

[137] Supplementation with aged garlic extract improves both NK and γδ-T cell function and reduces the severity of cold and flu symptoms: a randomized, double-blind, placebo-controlled nutrition intervention (2012): Nantz MP, Rowe CA, Muller CE, Creasy RA, Stanilka JM, Percival SS.

[138] Aged garlic extract supplementation modifies inflammation and immunity of adults with obesity: A randomized, double-blind, placebo-controlled clinical trial (2018): Xu C1, Mathews AE1, Rodrigues C1, Eudy BJ1, Rowe CA1, O'Donoughue A1, Percival SS2.

[139] Garlic Lowers Blood Pressure in Hypertensive Individuals, Regulates Serum Cholesterol, and Stimulates Immunity: An Updated Meta-analysis and Review (2016): Ried K

[140] The antioxidant, immunomodulatory, and anti-inflammatory activities of Spirulina: an overview (2016): Wu Q, Liu L, Miron A, Klímová B, Wan D, Kuča K.

[141]Well-tolerated Spirulina extract inhibits influenza virus replication and reduces virus-induced mortality (2016): Chen YH, Chang GK, Kuo SM, Huang SY, Hu IC, Lo YL, Shih SR

[142] Oral administration of a Spirulina extract enriched for Braun-type lipoproteins protects mice against influenza A (H1N1) virus infection (2015): Pugh ND, Edwall D, Lindmark L, Kousoulas KG, Iyer AV, Haron MH, Pasco DS.

[143] Antioxidant, Immunomodulating, and Microbial-Modulating Activities of the Sustainable and Ecofriendly Spirulina (2017): Finamore A1, Palmery M2, Bensehaila S3, Peluso I1.

[144] Effects of superfoods on risk factors of metabolic syndrome: a systematic review of human intervention trials (2018): van den Driessche JJ1, Plat J1, Mensink RP1.

[145] Nutraceuticals have potential for boosting the type 1 interferon response to RNA viruses including influenza and coronavirus (2020): Mark F.McCarty, James J.DiNicolantonio




[150] Can Chinese Medicine Be Used for Prevention of Corona Virus Disease 2019 (COVID-19)? A Review of Historical Classics, Research Evidence and Current Prevention Programs (2020): Luo H1,2, Tang QL3, Shang YX2,3, Liang SB2,3, Yang M2,3, Robinson N2,4, Liu JP5,6

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