Hydrapharm Science: Performance Through Precision Engineered Supplements

At Hydrapharm, we don’t chase trends. We build what others can’t. Our product development is guided by one principle: efficacy backed by chemistry, not marketing hype.

This isn’t the kind of science you’ll find in generic formulas with pixie-dusted actives or kitchen-sink blends. We use pharmaceutical delivery technologies - hydroxypropyl beta-cyclodextrins (HPβCDs), co-crystals, and peptide stabilisers - to radically upgrade how ingredients are absorbed, metabolised, and utilised. Then we pair those formats with novel actives and dosing decisions backed by pathway logic, not fairy dust.

This is where pharmacology meets performance.

1. Ingredient Innovation: What We Use That They Don’t

These aren’t label decorations — they’re the backbone of why our products perform:

Ingredient	What Makes It Special	Used In
7-Hydroxy-4-imidazolylflavan (HPβCD complexed)	127x stronger aromatase binding than aminoglutethimide. The most potent testosterone boosting compound to date for long term natural testosterone increases.	Alchemy
9-Methyl-β-carboline (9-MBC)	Rare dopamine-regulating compound with neuroprotective and neurogenic potential. Rarely seen in commercial products	9-MBC
SLU-PP-332	Mitochondrial uncoupling agent that increases energy expenditure, promotes endurance and enhanced fat oxidation at the cellular level without stimulant activity.	Mitolytic
Bromantane	Atypical adaptogenic stimulant originally developed for fatigue resistance and cognitive endurance. Distinct from caffeine-based stimulants due to its dopaminergic and anxiolytic profile.	Bromantane
Mineral Bisglycinates	High-dose bisglycinate minerals combined with glycine and L-theanine for superior absorption and sleep-stage support, rather than basic ZMA ratios focused only on deficiency correction.	ZMA Pro
Safranal (HPβCD complex)	Bioactive from saffron with clinical mood & cognition benefits; rarely stabilised in capsule form	Revival
7-Keto-DHEA HPβCD complex	Engineered with HPβCD to improve oral uptake and consistency. Targets metabolic pathways for greater fat loss than uncomplexed 7-OXO.	7-OXO Pro
Hydrazine (Proprietary Blend)	Underground legend: extreme tunnel vision, euphoric energy, Craze-like intensity	Hydrazine
NSI-189	Experimental neurogenesis-enhancing compound targeting hippocampal volume	Neurogenesis
Emoxypine	GABAergic antioxidant developed in Eastern Europe for stress resilience and cognitive protection.	Emoxypine & Revival
Oxymatrine (HPβCD complex)	Rare anti-inflammatory, glucose management bioactive made bioavailable via HPβCD complexation.	Elixir Pro
Anatabine (HPβCD complex)	Rare alkaloid modulating inflammation pathways; HPβCD boosts bioavailability	Anatabloc
Salidroside 99%	Ultra-pure Rhodiola extract supporting mitochondrial health, cognition, and stress resistance. Industry-leading purity (most brands = 1–3%)	Salidroside
5-Amino-1MQ (HPβCD complex)	Metabolic activator supporting NAD⁺ levels, AMPK activation, and body recomposition.	Lioptrope
Engineered Peptides (BPC-157, Ac-SDKP, Ac-LKKTETQ)	Regenerative peptides with new versions coming stabilised with multiple absorption enhancing technologies to greatly improve delivery, survive digestion and reach target tissues.	Unbreakable Pro

All of this is real, not theoretical. Most of these compounds are nowhere else in the UK market.
We use them not to impress — but because they work.

2. Delivery Formats That Change the Game

HPβCD Complexes: The Absorption Shield

Your Gut Is the Enemy - HPβCD Is the Armour

Hydrapharm uses hydroxypropyl-beta-cyclodextrin (HPβCD) to molecularly encapsulate unstable or poorly absorbed compounds, shielding them from degradation in the stomach and dramatically improving their solubility.

This isn’t just “better uptake” — it’s pharma-grade protection for ingredients that would otherwise fail.

Mechanism:

• Forms an inclusion complex around actives
• Shields from stomach acid and enzymes
• Enhances absorption by 2–4x, with cleaner plasma curves
• Used in: Adamantine Pro, Elixir Pro, Anatabloc, 7-OXO Pro, Lipotrope

Co-Crystals: Synergy at the Molecular Level

Why Pairing Molecules Isn’t Just Smart - It’s Superior

Co-crystallisation doesn’t just mix actives - it restructures them into a shared crystalline lattice, allowing them to behave as a single, more stable and absorbable unit.

Hydrapharm uses this method to amplify synergy, solubility, and shelf-life, often improving both potency and pharmacokinetics.

Advantages:

• Enhanced solubility (up to 3x)
• Improved stability in harsh environments
• Predictable, uniform delivery
• Used in: Adamantine Pro + more to follow

Nanoformulation: The Apex Delivery System

What If Your Supplement Could Bypass Digestion Entirely?

Hydrapharm’s nanoformulated compounds aren’t just “better absorbed” - they’re engineered to skip the bottlenecks that ruin most supplements: gastric breakdown, low permeability, and hepatic metabolism.

Nanocarriers shrink bioactives to sub-100nm size, allowing them to:

• Engineered for ultrafine particle size, enabling fast penetration and efficient delivery.
• Penetrates cellular membranes with ease
• Be absorbed through the oral mucosa, skin, or GI tract
• Improves absorption, bioavailability, with enhanced delivery to both targeted tissues and systemic circulation.
• Deliver higher potency at lower doses
• Used in: Coming soon across multiple Hydrapharm products

Armoured Peptides: Built to Survive

Peptides That Don’t Get Destroyed by Digestion

Many peptide supplements are nearly worthless — most get broken down before they can do anything. Hydrapharm solves this by pairing peptides with protective agents with new formulas coming soon ensuring even peptides with near zero oral effectiveness are able to have their structures protected, ensuring they reach systemic circulation intact.

This turns peptides from fragile molecules into high-performance bio-tools, fit for oral and alternative delivery methods (we have a suite of products coming featuring this capability).

Our Edge:

• Protective shields from gastric and liver breakdown
• New formulas which block enzymatic degradation
• Can be repurposed for multiple delivery methods
• Used in: Coming soon to Unbreakable Pro and more

3. Why Others Can’t Copy This

• They don’t have access to our supply chain.
• They don’t work directly with specialist labs able to synthesise novel compounds.
• They don’t use pharma techniques like nanoformulation, HPβCD inclusion, co-crystallisation, or ethanol-based peptide vehicles.

That’s why you’ll never find combinations like ours anywhere else in UK or US markets today.

4. What It Means for You

Hydrapharm’s formulas aren’t built in a marketing room. They’re built like pharmaceutical delivery systems, with stacked mechanisms:

• Higher bioavailability → lower required dose
• Rare actives → greater effect differentiation
• Stabilised formats → consistent performance

The result is measurable effects, not just hype.

5. Real-World Application (And What’s Next)

Adamantine Pro: HPβCD + co-crystals + PA deliver a triple-path muscle gain strategy.

Unbreakable Elite: You will see the ultimate in supplement science in one product when this groundbreaking formula lands.

Alchemy Pro: Bloodwork below shows elevated testosterone markers with 7-Hydroxy-4-imidazolylflavan with Alchemy and we now have something even more advanced coming soon.

Supporting Evidence

• Age: 47
• Prior Use: Androtest for 1 month leading to severely suppressed testosterone once removed
• PCT: Alchemy used by itself for just 3.5 weeks
• Testing Conditions: Severe jet lag + sleep deprivation after a long haul flight
   

Marker	Result	UK Range (pmol/L)	USA Equivalent (ng/dL)
Total Testosterone	29.2 nmol/L	8.64–29.0	~842 ng/dL
Free Testosterone	0.481 pmol/L	0.2–0.62	Top quartile
LH	9.1 IU/L	1.7–8.6	Elevated
FSH	8.82 IU/L	1.5–12.4	Normal

View Bloodwork Results

Coming soon:

• An even more potent testosterone booster than Alchemy
• Nanotech based products to unlock blood brain barrier penetration and deliver precision targeting of existing performance boosters
• Next-gen myostatin inhibitors